We’re here to help you identify the best NMN supplement on the market, one ideally designed to assist users in reducing many of the typical deteriorations that come with aging.
We’ve spent countless hours examining the market and believe Genuine Purity Liposomal NMN is the best NMN supplement available, and we’ll tell you exactly why below.
However, we’ll also lay out another 4 high-level options, which may also help you to look, feel, and think younger.
Have the ever-spinning wheels of time caught up with you? Are you often feeling exhausted, irritable, and simply fed up with everything? Maybe you’ve tacked on a few pounds or lost physical strength and can’t seem to get back in shape, no matter what you do?
If you’re “middle-aged” (or older) and answered yes to some or all of these questions, don’t fret because eye-catching new studies have reported that NMN supplementation and the subsequent growth in NAD+ synthesis can tremendously improve how well you age.
So much so that using the best NMN supplement has been reported to help users feel as much as 10-20 years younger in just a matter of weeks.
The Best NMN Supplement—The Pick Is In
Choosing which NMN supplement is truly the best of the best was no easy task.
Our team scrutinized ingredient lists, read scientific studies, examined user reviews, heard from experts, checked manufacturing practices, looked at satisfaction guarantees, noted affordability, and explored other related factors before coming up with our consensus rankings.
After all that, we’re confident we can present you with the top 5 dietary supplements designed to stimulate optimal aging outcomes.
They are:
- #1 Genuine Purity Liposomal NMN — Best Overall Anti-Aging Results
- #2 ProHealth Longevity NR Pro 500—Best For Supporting Cell Detoxification
- #3 Tru Niagen—Best For Highly Stressed Individuals
- #4 Thorne NiaCel 400—Best For Promoting Athletic Performance
- #5 aSquared Nutrition Nicotinamide—Best For Affordability
We’d recommend Genuine Purity Liposomal NMN for anyone interested in receiving reliable all-natural assistance to reduce age-induced health decline (both mental and physical).
Thanks to its high-quality NMN molecules and liposomal delivery system, this supplement gets the job done, fostering excellent cellular maturation for older adults. It’s the clear choice for the best NMN supplement.
That being said, all the products on this list deserve respect for the impressive age-defying benefits they may provide.
NMN Molecules, NAD+ Synthesis, And Aging
An organic nucleotide, NMN (nicotinamide mononucleotide), is the principal precursor to the vital life-sustaining molecule NAD+ (nicotinamide adenine dinucleotide). In other words, NMN naturally sparks NAD+ production through a series of biochemical reactions.
NAD+ is found in every cell in the human body. It’s crucial for powering your mitochondria, the tiny organelles that act as “powerhouses” for trillions of your cells.
In recent years, breakthrough studies have reported that maintaining ample NAD+ levels may be the key to healthier aging and reduced cellular degradation.
That’s likely because adequate NAD+ production is necessary to help nurture:
- Quality Sleep Cycles
- Good Blood Flow
- Metabolic Efficiency
- Joint Wellness
- Capably Strong Muscles
- Healthy Libido
- Cognitive Wellness
- Positive Mood & Mentality
- Immune System Efficiency
- Consistent Daily Energy & Focus
- DNA Repair
Sadly, as we get older, our NAD+ levels decline sharply. In fact, by the time most of us are in our 40s, 50s, and 60s, we’ll have less than half the NAD+ we had in our youth. This could be the primary reason we must endure substantial age-induced degeneration.
The good news is supplementing with NMN has been shown to aid in naturally restoring healthier NAD+ synthesis. While other compounds, like nicotinamide riboside (NR), can also be used to bring about NAD+ production, scientific studies report NMN is the most efficient natural NAD+ precursor.
According to a clinical review published in Integrative Medicine: A Clinician’s Journal, when ingested orally, NMN is absorbed and transformed into NAD+, triggering improved mitochondrial health, neuronal wellness, and greater longevity.
#1 Genuine Purity Liposomal NMN—Best Overall Anti-Aging Results
Genuine Purity Liposomal NMN takes the crown as the overall best NMN supplement. For several years, this 100% natural formulation has been helping men and women feel significantly younger, full of youthful vigor and clear-headedness.
If you’re searching for the mythical “fountain of youth,” it’s likely that Genuine Purity Liposomal NMN is the closest thing you’ll find in the real world.
The natural, organic dietary aid has no reported negative side effects but boasts loads of success stories for helping users “turn back the clock.”
Key Attributes
There are many reasons, such as its highly pure NMN molecules and the elite liposomal delivery system, to believe Genuine Purity Liposomal NMN is the best NMN supplement.
Plus, the scientific substantiation backing the formula suggests premier anti-aging benefits are likely to occur within 4-6 weeks of daily use.
Contains High Purity NMN (β-Nicotinamide Mononucleotide 98%)
Evidence shows NMN is the premier precursor to NAD+. That’s because NMN is directly converted into NAD+ through an enzymatic reaction in your body.
Other NAD+ precursors like nicotinamide riboside (NR) must undergo multiple alterations before becoming NAD+, making them less efficient.
Genuine Purity Liposomal NMN contains 98% pure NMN molecules. Generally, NMN with higher than 95% purity is considered high quality. This supplement blows that number out of the water.
Studies show NMN purity is a critical factor in the success of any NMN supplement. Higher purity brings greater bioavailability, increased direct cell targeting, and more efficient results.
The NMN in Genuine Purity Liposomal NMN is third-party tested. So, you don’t have to take our word for it. The proof is in the science. Genuine Purity will provide a third-party test certification upon request.
Liposomal Delivery System Promotes Enhanced Absorption
Historically, the chief issue with NMN supplementation has been the relatively low absorption rates NMN compounds demonstrate in humans.
You see, when you ingest NMN orally, especially low-purity NMN molecules, your stomach acids, and digestive enzymes immediately go to work, breaking a large percentage of them down.
As a result, much of NMN’s nourishing value gets “flushed away,” never reaching the bloodstream, where it must be to affect aging positively.
Genuine Purity Liposomal NMN utilizes a liposomal protection system that defends its valuable NMN particles against corrosive stomach acids and digestive enzymes.
Liposomal protection systems are relatively common in pharmaceuticals and high-end vitamins. The system employs tiny lipid-based spherical vessels resistant to stomach acids and digestive enzymes.
Thus, critical ingredients are “shielded,” allowing more to enter the bloodstream and cells throughout the body.
The same is true with Genuine Purity Liposomal NMN. The liposomal protection system helps to ensure higher NMN absorption rates for substantially greater anti-aging outcomes.
100% Satisfaction Guarantee Provides Excellent Reassurance
The makers of Genuine Purity Liposomal NMN are so confident in their supplement that they’re willing to put their money where their mouth is.
When you order Genuine Purity Liposomal NMN through the manufacturer’s official website, you’ll get a 90-day money-back satisfaction guarantee.
If, for whatever reason, you’re unhappy with your experience using the supplement, simply send it back. You’ll receive a refund of the purchase price for all used and unused bottles.
Essentially, you’ll be given a 90-day “free trial” to determine whether Genuine Purity Liposomal NMN works for you.
However, it appears the return rates on this product are quite low. So, it would seem most users are thrilled with the anti-aging benefits it aids in stimulating.
Reported Benefits
The reports of successful anti-aging outcomes with Genuine Purity Liposomal NMN are numerous and widespread.
With a healthy serving of high-quality NMN (98% pure), made highly absorbable thanks to liposomal protection, and a 100% satisfaction guarantee, it’s apparent Genuine Purity Liposomal NMN is a force to be reckoned with.
Genuine Purity Liposomal NMN should aid in:
- Improving Sleep Quality
- Upgrading Libido
- Boosting Daily Energy Levels
- Optimizing DNA Repair
- Speeding Up Metabolic Efficiency
- Enhancing Body Composition
- Strengthening Immune System Wellness
- Supporting Better Memory, Focus, & Mindset
- Promoting Enhanced Moods & Outlook
Supplying clean, unadulterated NMN with greater bioavailability Genuine Purity Liposomal NMN may provide you with these benefits in just 4-6 weeks. Some users even report improvements in as little as 2 weeks.
How To Use
Not only does Genuine Purity Liposomal NMN contain the ingredient makeup indicative of the best NMN supplement, but it’s also incredibly easy to use.
All you have to do is take 1 small vegetable cellulose capsule per day. It’s best to take the capsule with a meal of your choice to help the digestive process.
Genuine Purity Liposomal NMN is designed to be taken daily. And the results are cumulative. So, the longer you use it, the more prosperous your wellness can grow.
However, it’s important to note that, as with all the best NMN supplements, you’ll need to continue using the supplement to continue achieving anti-aging results.
Manufacturer
Genuine Purity, the manufacturer of Genuine Purity Liposomal NMN, has been designing and manufacturing elite health supplements for over 20 years.
During that time, they’ve earned a reputation for reliability, success, and excellent customer service.
So, it’s really no surprise they’d make what we believe is the best NMN supplement in the world.
Genuine Purity Liposomal NMN is:
- Made In The USA
- Manufactured in cGMP-Certified Facilities
- Organic
- GMO-Free
- Gluten-Free
- Soy-Free
- Egg-Free
- Sugar-Free
- Dairy-Free
- Wheat Grain-Free
- Preservative-Free
You can rest easy knowing that Genuine Purity Liposomal NMN is manufactured in the USA, inside cGMP-certified facilities, adhering to the strictest FDA regulations.
These standards indicate you’ll get a consistently high-quality supplement with no known negative side effects.
Affordability
A 2-month supply (1 bottle of 60 capsules) costs $69.95.
When you buy in bulk, you’ll save some money.
For example:
- Buy 3 Bottles, Pay $66.65 Per Bottle (6-Month Supply)
- Buy 6 Bottles, Pay $58.33 Per Bottle (12-Month Supply)
These prices are available on the official Genuine Purity Liposomal NMN homepage.
There, you’ll also find free shipping in the continental USA.
Pros & Cons
We love what Genuine Purity Liposomal NMN brings to the table in the ongoing battle against age-related decline. And we think you will, too.
However, nothing is totally perfect, and everyone’s situation is different. With that in mind, we’ll run down the pros and cons.
Pros
- Contains β-Nicotinamide Mononucleotide 98% (Highly Pure NMN)
- Uses Liposomal Protective Delivery System For Better Absorption
- Comes With A 90-day Money-Back Satisfaction Guarantee
- Ingredients Have Scientifically Substantiated Benefits
- 100% Natural & Organic Formula
- Made In The USA
- Manufactured in cGMP-Certified Facilities
- Competitively Priced & Savings On Bulk Orders
- Free Shipping In The Continental USA
Cons
- Only Available For Purchase Online
As you see, the pros of Genuine Purity Liposomal NMN tremendously outweigh the cons. However, you can only order the supplement online, which may pose a problem for some.
Where To Purchase
We’d recommend purchasing Genuine Purity Liposomal NMN through the official website.
That’s where you’ll find the best prices, the 90-day money-back guarantee, free shipping in the lower 48 of the USA, and excellent customer service.
#2 ProHealth Longevity NR Pro 500—Best For Supporting Cell Detoxification
ProHealth Longevity NR Pro 500 comes in second, just behind the best NMN supplement.
And while this product technically doesn’t contain NMN in its formula, it has the next best thing. That is the precursor to NMN known as nicotinamide riboside (NR).
Key Attributes
There are a couple of reasons why ProHealth Longevity NR Pro 500 should help users age more gracefully.
Contains Nicotinamide Riboside (NR)—The NMN Precursor
While ProHealth Longevity NR Pro 500 can’t provide you with highly pure NMN molecules, it can give you a serving of NR that should help to stimulate NMN synthesis and eventually NAD+ production.
Like NMN, NR has gained recognition for some powerful anti-aging benefits in recent years. However, it may require more internal energy consumption to achieve similar results.
Incorporates Trimethylglycine (TMG)
A biological compound, sometimes called betaine, trimethylglycine (TMG) doesn’t directly support NAD+ synthesis but can help your cells detoxify and enhance your mental outlook.
Known as a “methyl donor,” TMG helps your body transform internal toxins into less detrimental, even usable compounds.
As a result, the TMG can also help to enhance liver wellness and upregulate the activity of neurotransmitters like dopamine.
Reported Benefits
With a solid combination of NR and TMG, ProHealth Longevity NR Pro 500 may assist in mitigating several downsides that occur due to us getting older.
ProHealth Longevity NR Pro 500 should aid in:
- Lowering Some Toxin Levels
- Boosting Cellular Wellness
- Enhancing Blood Flow
- Supporting Better Mindset
- Promoting Greater Body Composition
Thanks to the increased synthesis of NMN eventually stimulating more NAD+ production, plus the detoxifying effects of TMG, ProHealth Longevity NR Pro 500 is capable of bringing reliable rewards for anti-aging.
How To Use
It’s recommended to swallow 2 capsules per day, preferably with food, for the best results.
As with all health supplements, be sure to discuss any new usage with your physician before diving in head first.
Manufacturer
ProHealth manufactures and distributes ProHealth Longevity NR Pro 500.
They’ve been building good health supplements for just over 30 years, garnering a reputation for dependable outcomes.
ProHealth Longevity NR Pro 500 is:
- Made In The USA
- Manufactured In cGMP-Certified Facilities
- Dairy-Free
- Soy-Free
- Gluten-Free
- Third-Party Tested
It’s reassuring to know that the manufacturer has been in the health supplement industry for multiple decades. This fact tells us they’re committed to building successful supplements.
Affordability
A 1-month supply (1 bottle of 60 capsules) sells for $58.46.
Savings may be available when you subscribe for recurring purchases.
Pros & Cons
ProHealth Longevity NR Pro 500 should supply some significant enhancements to assist you in aging ideally.
However, it’s not the best NMN supplement for a few reasons.
Pros
- Incorporates Trimethylglycine (TMG) To Support Cellular Detox
- Has Nicotinamide Riboside (NR) To Stimulate NMN Numbers
- Made In the USA
- Manufactured in cGMP-Certified Facilities
- Well-Respected Manufacturer
Cons
- Contains No NMN Molecules
- Above Average Cost For NR
- No Savings Available
ProHealth Longevity NR Pro 500 is in the conversation for the best NMN supplement, but it also has several issues, as you see listed here.
Where To Purchase
We’d recommend Amazon for great deals on ProHealth Longevity NR Pro 500.
#3 Tru Niagen—Best For Highly Stressed Individuals
Tru Niagen ranks third in the race for the best NMN supplement.
This product uses Niagen, a form of nicotinamide riboside (NR), reported to help induce NMN production and increase NAD+ levels.
It may be ideal for individuals regularly experiencing high stress, a massively damaging force in the aging process.
Key Attributes
There are several aspects of Tru Niagen that suggest it belongs among the best supplements for NAD+ support.
Contains Niagen (Patented Nicotinamide Riboside Compound)
Tru Niagen contains the compound Niagen. A form of NR, Niagen holds a patent and is used in numerous NAD+-promoting health supplements.
Again, this supplement doesn’t contain actual NMN molecules, but this might be the next best option in anti-aging science.
Niagen could be especially adept at activating antioxidant enzymes that help to lower oxidative stress in some cells.
Good Sales Record
Tru Niagen boasts a solid sales record, indicating many users are rebuying it. Generally speaking, this shows people are reaping some rewards and tolerating a supplement well.
According to the manufacturer, “Thousands of customers report overall improvements in general health and well-being.”
While reportedly good sales numbers aren’t the end-all-be-all for effective dietary aids, they do at least suggest successful outcomes.
Reported Benefits
Comprised of a single ingredient, a serving of Niagen, Tru Niagen could help users age better and reduce some stress-induced problems.
Tru Niagen should aid in:
- Stimulating Antioxidant Activity
- Repairing Damaged DNA
- Increasing Cellular Energy
- Lowering Stress Levels
- Supporting Metabolic Wellness
If you’re often “stressed out” and feel it’s making you age faster biologically, Tru Niagen might be a good fit for you.
How To Use
Tru Niagen is simple to use, requiring just 1 capsule per day.
The manufacturer recommends taking each serving with some food for optimal digestion.
Manufacturer
Tru Niagen’s manufacturer shares its namesake (Tru Niagen).
The company primarily focuses on making this one supplement. However, they do make another dietary product designed to build immune system wellness, which has gained some traction in the market.
Affordability
A 1-month supply (1 bottle of 30 capsules) costs $42.57.
You can save money when you order 2+ bottles.
For example:
- Buy 2 Bottles, Pay $39.58 Per Bottle (2-Month Supply)
- Buy 3 Bottles, Pay $38.99 Per Bottle (3-Month Supply)
Free shipping may be available for some when you sign up for recurring monthly orders.
Pros & Cons
Tru Niagen, by most accounts, should be a good supplement to help in the fight against aging, especially when hastened deterioration results from high stress.
However, it’s not going to be the best NMN supplement for everyone.
Pros
- Contains Patented Form Of Nicotinamide Riboside (NR)
- Boasts Good Track Record Of Sales Success
- Could Aid In Stimulating Antioxidants
- Savings Available On Bulk Orders
- Free Shipping Available On Some Orders
Cons
- Manufacturer History Is Somewhat Limited
- No Clear Satisfaction Guarantee
- Lacking NMN Molecules
Where To Purchase
Amazon supplies the best deals and shipping rates for Tru Niagen.
#4 Thorne NiaCel 400—Best For Promoting Athletic Performance
Thorne NiaCel 400 comes in fourth, just a few places behind the overall best NMN supplement.
Another product with zero NMN molecules, Thorne NiaCel 400, employs a “special” NR compound to help users boost NAD+ and maximize physical fitness.
This supplement might be suitable for “middle-aged” athletes who need an extra performance boost.
Key Attributes
Thorne NiaCel 400 is a fine choice for men and women who want to stay in the game. And there is some reliable evidence to back that up.
Contains Nicotinamide Riboside Hydrogen Malate
The “special” form of NR found in Thorne NiaCel 400 is called Nicotinamide Riboside Hydrogen Malate (NRHM).
This unique variant of the compound combines NR with hydrogen malate, a salt compound formed from malic acid (an acid found in many fruits).
Reported Benefits
Thanks to a solid serving of NRHM, Thorne NiaCel 400 may enhance athletic performance for physically active older adults.
Thorne NiaCel 400 should aid in:
- Improving Exercise Efficiency
- Promoting Cellular Energy
- Supporting DNA Repair
- Upgrading Muscle Strength
Suppose you like to “get after it” in the gym or on the field of play. In that case, Thorne NiaCel 400 may represent a great option to help keep you performing at a high level for years to come.
How To Use
Users should take 1 capsule 1-2 times per day, depending on needs.
The manufacturer recommends discussing what’s best for you with your physician.
Manufacturer
As stated above, Thorne NiaCel 400 is manufactured by Thorne.
This company has amassed a reputation for helping athletes to reach their full potential. All their supplements are manufactured in the USA.
Thorne NiaCel 400 is:
- Manufactured in cGMP-Certified Facilities
- NSF Sport-Certified
- Used By CrossFit Athletes
In this case, the manufacturer's reliability is solid, suggesting prominent benefits can be achieved without known negative side effects.
Affordability
A 2-month stock (1 bottle of 60 capsules) goes for $61.20.
However, if you choose to take 2 capsules per day, this only amounts to a 1-month supply.
Savings may be available for some individuals when you sign up for monthly recurring orders.
Pros & Cons
Thorne NiaCel 400 has gained a following among active individuals who aren’t willing to give up the physical activities they love just because of age.
That said, this supplement ranks fourth on our list and won’t be the best NMN supplement for all.
Pros
- Uses “Special” Form Of Nicotinamide Riboside (NRHM)
- Made By A Reliable Manufacturer
- Manufactured In The USA
- Good Scientific Substantiation
- Trusted By Athletes
Cons
- Zero NMN Molecules
- No Enhanced Absorbability System
- Above Average Price For NR Supplement
Where To Purchase
Amazon provides the lowest prices on Thorne NiaCel 400.
They also supply cost-free shipping on some orders.
#5 aSquared Nutrition Nicotinamide—Best For Affordability
The fifth product on our list is aSquared Nutrition Nicotinamide.
This longevity-promoting supplement employs Vitamin B3 and resveratrol to help users promote better daily energy and wellness.
While it doesn’t utilize high-value NMN, aSquared Nutrition Nicotinamide could still help to stimulate NAD+ synthesis.
Key Attributes
The proprietary aSquared Nutrition Nicotinamide formulation comprises a couple of well-known NMN and NAD+ precursors that may combine to help you age “like a fine wine.”
Contains Reservatrol
A bioactive compound highly concentrated in the skin of red grapes, resveratrol helps to support many aspects of health, especially some of those most negatively affected by aging.
The compound is known to have strong antioxidant properties, helping to reduce inflammation and oxidative stress in human cells.
Reported Benefits
Using the relatively potent combination of nicotinamide and resveratrol, aSquared Nutrition Nicotinamide can deliver some NAD+ enhancements and anti-aging benefits.
aSquared Nutrition Nicotinamide should aid in:
- Boosting Daily Energy
- Reducing Oxidative Stress
- Supporting Longevity
- Enhancing Immune Wellness
How To Use
aSquared Nutrition Nicotinamide couldn’t be easier to use.
It requires just 1 capsule per day, preferably taken with a meal to optimize uptake.
Manufacturer
aSquared Nutrition manufactures aSquared Nutrition Nicotinamide in the USA.
This company recently went through a complete revamping, adding 20 health supplements to their line.
It might be that the “jury is still out” on this transformation, but it does appear they’re designing some quality all-natural products.
Affordability
A 4-month supply (1 bottle of 120 capsules) costs $27.95.
When you sign up for recurring purchases, you can save even more.
Pros & Cons
Look, aSquared Nutrition Nicotinamide may help to produce rejuvenation and marginally better NAD+ levels.
That said, it may not be the most efficient supplement on the market, especially for those individuals who are unrelentingly serious about aging well.
Pros
- Extremely Affordable
- Contains Reservatrol
- Uses “Flush-Free” Nicotinamide
- Made In the USA
- Vegan-Friendly
Cons
- Lacks NMN
- Lacks NR
- No Satisfaction Guarantee
Where To Purchase
aSquared Nutrition Nicotinamide is available for the low price seen above on Amazon.
They also promote savings deals on recurring buys and free shipping for some customers.
The Best NMN Supplement Could Help You To Feel 10-20 Years Younger
Getting older is never a fun ride. We’re all facing some level of mind, body, and soul decay. Sadly, that’s just what “Father Time” and “Mother Nature” have given us.
Recent studies show that NAD+ decline is a primary reason we experience this degradation. Further studies have shown NMN supplementation can be the most efficient way to restore youthful NAD+ synthesis.
Therefore, using the best NMN supplement might help you feel up to 10-20 years younger mentally and physically.
Our research indicates that Genuine Purity Liposomal NMM is the best NMN supplement available. We’d highly recommend giving it a try.
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Note- This article is written by Brand Desk.