
In a society where hard work and burning the midnight oil are celebrated, sleeping and resting well usually takes the back seat. While many of us think we can catch up on sleep over the weekend, our mind and body gets stuck in the loop of sleep debt, which can quietly damage our vital organs. According to health experts, apart from making us grumpy or irritable, lack of sleep can also affect our hormones, cardiovascular system, as well as our kidneys.
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In an exclusive interaction with the editorial team of Onlymyhealth, our expert, Dr Brunda M S, Senior Consultant - Internal Medicine, Aster CMI Hospital, Bangalore, explained that lack of sleep can trigger the start of a chain reaction within one's body, thereby influencing bodily systems that play an important role in maintaining overall health. Read ahead to know everything she shared with us.
What is Sleep Debt?
According to Science Direct, sleep debt can build up when the body when it chronically fails to get the adequate amount of sleep it requires, which is usually less than 7 to 8 hours for most adults. A single night of staying up late may not catch up, but a sleep debt gradually develops.
In the words of Dr Brunda, “Sleep debt is the lack of sleep over a period of days and can impair the body. A lot of people may not know the effects because they may be gradual.”
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Link Between Sleep Debt and Hormone Imbalance
Hormonal system is one of the first to experience the effects of poor sleep. The body uses sleep to control the most crucial hormones involved in hunger, stress, and regulating blood sugar levels.
"Sleep deprivation affects hunger hormones such as leptin and ghrelin. It causes a person to feel hungry and trigger an appetite for high caloric foods. This causes a person to gain weight, which further causes insulin resistance, type 2 diabetes, and other chronic conditions,” Dr Brunda explained.
Lack of sleep also leads to an increase in cortisol, which is referred to as the primary stress hormone in the body. High levels of cortisol in the body cause mood swings, anxiety, poor focus, as well as various metabolic problems.
Affect of Sleep Debt on Heart
Sleeping gives the heart an opportunity to rest. When sleep time is interrupted, it means the heart will always be under stress.
“It can raise stress hormones, such as cortisol, which raises blood pressure that makes the heart work too hard,” Dr Brunda added. All these can lead to hypertension, arrhythmias, coronary artery diseases, and even stroke.
Research indicates that individuals with chronic sleep disorders tend to develop cardiovascular diseases, especailly when they are either physically inactive or smoke.
Affect of Sleep Debt on Kidneys
The connection between sleep and heart problems has received wide attention, however, there is only a little consideration given to the effect of sleep issues on kidney problems. The kidneys need normal blood pressure and hormonal levels to be in optimal condition.
“Sleep debt influences kidneys by interrupting the regulation of blood pressure and decreasing the ability of the body to manage fluids and remove wastes,” Dr. Brunda highlighted. Those who lack enough sleep have higher risks of experiencing damage to kidneys, particularly those who have diabetes or high blood pressure.

Poor sleep can also worsen existing kidney problems because it affects the body’s natural overnight process of repairing and keeping the kidneys healthy.
Impact of Sleep Debt on Immunity and Healing
In addition to the hormonal, heart, and kidneys, the immune system becomes compromised due to lack of sleep, which causes an people to fall ill more often and take longer to heal when sick or injured. It also results in an inefficient healing process because the body takes longer to heal.
Why Quality Sleep Is Non-Negotiable
Experts suggest that regular, adequate sleep is one of the simplest yet most powerful tools for disease prevention.
“Getting regular sleep of seven to eight hours helps in the proper functioning of hormones, keeps the heart healthy, and safeguards the kidneys. Good sleep is not a luxury, but a basic requirement of everyday life,” Dr Brunda emphasised.
Easy practices such as keeping a regular sleep pattern, avoiding screens before sleeping hours, limiting caffeine consumption, and optimising a sleeping environment can do wonders in overcoming sleep debt.
Bottomline
Chronic sleep debt quietly disrupts hormones, increases heart disease risk, and impairs kidney function. Expert suggest prioritising consistent, quality sleep is essential for protecting long-term health.
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FAQ
1. Can weekend sleep make up for sleep debt?
Not entirely. While an additional amount of sleep can lower fatigue, it cannot fully reverse sleep deficiencies.2. How many hours of sleep do adults need?
Most adults require seven to eight hours of quality sleep each night for optimal hormonal, cardiovascular, and renal health.3. Who is most at risk from sleep debt?
People with diabetes, high blood pressure, heart disease, or high stress levels are especially vulnerable to the harmful effects of poor sleep.
How we keep this article up to date:
We work with experts and keep a close eye on the latest in health and wellness. Whenever there is a new research or helpful information, we update our articles with accurate and useful advice.
Current Version
Dec 23, 2025 15:41 IST
Published By : Tanya Srivastava