Amitiza is a medication for providing relief in idiopathic chronic constipation and irritable bowel syndrome. Lubiprostone, the main constituent of amitiza, aids in the increasing of intestinal fluid present in the intestines. As a result, the increased fluids assist in regulating the stool excretion process. Weight loss during amitiza intake may often occur as a result of the body’s reaction to the medication. Designed specifically to offer constipation relief, amitiza may lead to minor weight loss as it propels regular stool flow and aids in eliminating compacted faecal matter from the body which may add up to 10 pounds to the patient’s total weight. However, it is not advisable to use amitiza as a remedy to lose weight because it may lead to other complications in the body.