Study Reveals Popular Painkiller Tramadol Shows Minimal Pain Relief And Higher Heart Risk – Expert Decodes

Popping pills, even for the smallest of health issues, has become a common practice. Doctors have, time and again, warned people against its side effects. And this has yet again come to light after the popular painkiller tramadol has stirred controversy recently. As per a recent study, the opioid – which was considered a ‘safer’ painkiller – may not be as harmless as it may seem. Instead, tramadol may have higher heart risk as well. If you want to know more about the study, then this article is for you.

The editorial team of OnlyMyHealth reached out to Dr Tushar Tayal, Associate Director, Internal Medicine, CK Birla Hospital, Gurugram, to get a better understanding of whether tramadol is safe or not. Read ahead.

What Is The New Study On Tramadol All About?

Recent findings from a research was published online in BMJ Evidence-Based Medicine. As per the study, a large analysis of clinical trials found tramadol does reduce chronic pain, but the relief is modest. It added that patients likely wouldn’t notice much real-world benefit. At the same time, it stated that tramadol is linked to a significantly higher risk of serious side effects, especially heart-related issues like chest pain and heart failure, as well as common issues such as nausea, dizziness, and sleepiness.

Based on the research results, the study concluded that the risks associated with tramadol are likely to be greater than its benefits. The researchers even recommended that its use should be reduced.

What Is Tramadol?

First things first, let us get to know from our expert what tramadol actually is. “Tramadol is a frequently prescribed painkiller for moderate to moderately severe pain. But recent evidence suggests it may not be as safe or effective as once believed, especially when used long-term or without close medical supervision,” shares Dr Tayal.

He adds, “Tramadol works in two ways: it acts like an opioid to block pain signals. Secondly, it can also alter brain chemicals such as serotonin and norepinephrine. This dual action increases the risk of side effects and drug interactions.”

Is Tramadol Safe For Use?

Now, let us address the main question – whether tramadol is harmless or safe? “While tramadol may provide short-term pain relief for some people, studies show its benefit is often modest and unpredictable. More importantly, it carries significant risks.” On this note, Dr Tayal jots down some of its common side effects:

• Nausea.
• Dizziness.
• Constipation.
• Drowsiness.
• Headache.

The expert adds that more serious concerns include:

• Dependence.
• Withdrawal symptoms.
• Seizures (even at prescribed doses).
• Breathing problems, especially when combined with alcohol, antidepressants, or other sedatives.

“There is also growing evidence linking tramadol use to an increased risk of low blood sugar, confusion, falls in older adults, and serotonin syndrome, a potentially life-threatening condition,” explains Dr Tayal.

“Because tramadol is an opioid-like drug, it can lead to misuse and addiction, contrary to the earlier belief that it was relatively ‘safe’. Therefore, tramadol should only be used when clearly indicated, for the shortest possible duration, and under strict medical guidance. Patients should never self-medicate or increase doses without consulting a doctor,” concludes Dr Tayal.

The Final Word

Tramadol is a commonly prescribed painkiller for moderate to moderately severe pain. But recent evidence suggests it may not be as safe or effective as once believed, especially when used long-term or without close medical supervision. Tramadol should only be used when clearly indicated, for the shortest possible duration, and under strict medical guidance. Patients should never self-medicate or increase doses without consulting a doctor.