In a recent study, researchers found that two experimental Alzheimer's drugs, known as CMS121 and J147, may prove beneficial in improving a person's memory and slowing down brain cell damage. Research published in the journal E-Life suggests that these drugs can be quite beneficial for Alzheimer's patients. Although this research has been done on mice, scientists will soon be able to use it on humans too. Alzheimer's is a serious disease, which is spreading rapidly these days.
According to Pamela Maiher, a senior scientist at the Salk Institute for Biological Studies in the US and co-author of the study, "This study has revealed that both compounds ( CMS121 and J147) are not only used as Alzheimer's drugs But can also protect against damage to brain cells due to aging."
In this study, researchers have stated how both these compounds can delay aging in a healthy mouse and prevent further damage to the brain cells. Similar conditions are commonly seen in humans during aging.
Alzheimer's disease usually occurs in old age people. The onset of this disease is seen after the age of 65 in most people. The risk of increasing Alzheimer's disease in people above this age increases by 200% every five years.
In the new study, researchers turned to an abnormally fast aging strain in mice. In which a set of mice were given CMS121 and J147 at nine months of age. After 4 months of this, the team tested the recall and behavior of the mice and analyzed genetic and molecular markers in their brains. Which found that mice taking these drugs performed better in recall trials than untreated mice.
Researcher and study author Maihar said, "Both of these compounds inhibit molecular changes, which are associated with aging". However, more detailed experiments showed that both the drugs alter Mitochondria by augmenting the level of the chemical acetyl-coenzyme A or Acetyl-COA. It is necessary to tell you here that this study has been done on mice models, what will be the results of this research on humans, it will be clear only after further experimentation.
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