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Kidney Cancer: Causes, Diagnosis, Drawbacks of Conventional Surgery, and Treatment Options

Kidney cancer is a serious condition that requires prompt diagnosis and appropriate treatment.   
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Kidney Cancer: Causes, Diagnosis, Drawbacks of Conventional Surgery, and Treatment Options

Kidney cancer, also known as renal cancer, occurs when abnormal cells in the kidneys grow uncontrollably, forming a tumor. The kidneys are vital organs responsible for filtering waste products from the blood and producing urine. 

“There are different types of kidney cancer, with Renal Cell Carcinoma (RCC) being the most common type in adults. It is a concerning health issue that affects thousands of individuals worldwide each year,” said Dr Muralidhar Bora - Consultant Radiation Oncologist, HCG Cancer Centre, Vizag. 

“Healthcare providers diagnose approximately 400,000 new cases worldwide. Anyone can develop RCC, but it’s most common in men and commonly seen between 50 to 70 years of age.his article aims to provide a comprehensive overview of kidney cancer, including its causes, diagnosis, drawbacks associated with conventional surgery, and available treatment options,” Dr Bora said. 

Also read: World Kidney Cancer Day: Understanding Kidney Cancer, Its Symptoms, Diagnosis, And Treatment Options

Prognosis Of Kidney Cancer 

According to Dr Bira, the prognosis depends on the stage of histology of the cell type.

  • Stage 1: has a 90% 5-year survival rate.
  • Stage 2: has a 50% 5-year survival rate.
  • Stage 3: gas a 30 % 5-year survival rate.
  • Stage 4: has a 5% 5-year survival rate.

Causes of Kidney Cancer

“The exact cause of kidney cancer remains unclear, but several risk factors have been identified. These include smoking, obesity, high blood pressure, family history of kidney cancer, certain genetic conditions, exposure to certain chemicals or substances like asbestos or cadmium, and long-term dialysis treatment,” said Dr Bora. As per him following are the symptoms of kidney cancer. 

  • A lump on your side, belly, or lower back
  • Blood in urine
  • Low back pain on one side
  • Losing weight for no clear reason
  • Not feeling hungry
  • Fever
  • Feeling tired
  • Anemia 
  • Night sweats
  • High levels of calcium in blood
  • High blood pressure

Diagnosis

Early detection of kidney cancer is crucial for effective treatment and improved outcomes. Common diagnostic procedures for kidney cancer include imaging tests such as ultrasound, CT scans, MRI scans, and angiography. Biopsy may also be performed to confirm the diagnosis by examining a sample of kidney tissue under a microscope.

Drawbacks of Conventional Surgery

Conventional surgery for kidney cancer typically involves open surgery, known as a nephrectomy, where the entire kidney or tumor is removed through a large incision in the abdomen or side. While effective, conventional surgery has several drawbacks, including longer recovery times, increased risk of complications such as infection and bleeding, and longer hospital stays.

Treatment Options

Advancements in medical technology and surgical techniques have led to the development of alternative treatment options for kidney cancer, offering improved outcomes and reduced risk of complications. Some of these treatment options include:

1.Minimally Invasive Surgery

“In the modern method of treatment minimally invasive procedures, such as laparoscopic or robotic-assisted surgery, offer several advantages over conventional open surgery, including smaller incisions, less blood loss, faster recovery times, and reduced risk of complications,” Dr Bora said. 

2.Partial Nephrectomy

“In cases where the tumor is small and confined to a specific area of the kidney, a partial nephrectomy may be performed to remove only the tumor while preserving the healthy portion of the kidney. This approach helps to maintain kidney function and reduces the risk of long-term kidney problems,” Dr Bora said. 

3.Cryoablation and Radiofrequency Ablation

Dr Bora added that these minimally invasive procedures involve the use of extreme cold or heat to destroy cancerous tissue. They are often recommended for small tumors or patients who are not suitable candidates for surgery.\

4.Targeted Therapy and Immunotherapy

As per Dr Bora, targeted therapy drugs and immunotherapy drugs are designed to target specific molecules or pathways involved in cancer growth and spread. These treatments can be effective in advanced or metastatic kidney cancer cases and may be used alone or in combination with other treatments.

Also read: Kidney Cancer In Children: Types, Causes, Symptoms and Treatment

“Kidney cancer is a serious condition that requires prompt diagnosis and appropriate treatment. While conventional surgery has been the standard approach for many years, alternative treatment options such as minimally invasive surgery, partial nephrectomy, and targeted therapy offer promising outcomes with fewer drawbacks. It is essential for individuals at risk of kidney cancer to be aware of the symptoms and seek medical attention if they experience any concerning signs,” Dr Bora concluded. 

By staying informed and exploring all available treatment options, patients can make informed decisions about their care and improve their chances of successful outcomes.

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