Cleto Escobedo III, Jimmy Kimmel's Friend, Death Cause Cited To Be Complications Stemming From Liver Transplant - Report

News of Cleto Escobedo III’s death has left the late-night television world in shock. The 59-year-old was best known as the longtime bandleader for “Jimmy Kimmel Live!” and for his decades-long friendship with host Jimmy Kimmel. Cleto’s warm stage presence and saxophone skills made him a fan favourite since the show’s premiere. Known for his easy smile, musical talent, and undeniable chemistry with the host Kimmel, Escobedo was not just a bandleader; he was a vital part of the show’s soul.

Cleto Escobedo’s Cause of Death

 

 

 

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While the exact cause of Cleto Escobedo III’s death has not been officially confirmed, early reports suggest that it may have been linked to complications following a liver transplant. Several media outlets have cited unnamed sources close to the musician claiming that his health had been fragile in recent months. However, there has been no official statement from his family or the Jimmy Kimmel Live! team about the precise medical reason behind his passing.

Health experts often explain that liver transplant recovery can involve significant risks. Post-surgery complications such as infection, organ rejection, or liver failure can develop even after successful procedures. Though it’s not clear whether any of these applied to Escobedo, such possibilities highlight how delicate and unpredictable transplant recovery can be.

A study published in Liver Transplantation looked at 1,684 liver transplant recipients, both deceased-donor and living-donor, and found that nearly 38% of deceased-donor recipients and 47% of living-donor recipients experienced a major complication within 90 days, such as bile-duct leaks, bleeding needing surgery, or blood-vessel problems.

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Who Was Cleto Escobedo?

Raised in Las Vegas, Cleto met Jimmy Kimmel as a child, and the two grew up as close friends living across the street from one another. Their bond carried into adulthood, with Cleto becoming the heart of “Jimmy Kimmel Live!” for over two decades.

Apart from his television fame, Cleto toured with legends like Paula Abdul, Marc Anthony, and Phillip Bailey, and recorded with big names in the music world. 

Those who knew him recall his generous spirit, humour, and commitment to music and family. His father, Cleto Escobedo Jr., also played in the house band, making their journey uniquely special. Over the years, Escobedo’s charm and warmth made him a fan favourite. His lighthearted banter with Kimmel added a personal touch that few late-night shows could replicate. Behind the scenes, friends describe him as humble, grounded, and devoted to his family and music.

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Conclusion

Cleto Escobedo III’s passing is a reminder of how suddenly life can change, but also of the impact a single person can have through talent and kindness. While the world waits for official details, Cleto’s life stands as a tribute to music, friendship, and following your passion.