-1749817749853.webp)
In a surprising shift from its original purpose, Ozempic, a widely used weight loss drug —is now being linked to heart protection. Researchers have found that semaglutide, the drug’s active ingredient, may significantly reduce the risk of major cardiovascular events. Ozempic, aka Semaglutide, is a GLP-1 receptor agonist best known for its anti-obesity effects, and may now reduce the risk of heart attacks and strokes.
According to a recent study published in The New England Journal of Medicine, patients who received weekly doses of semaglutide showed a decreased risk of stroke, heart attack, and even death from cardiovascular diseases.
To better understand how Ozempic can contribute positively to heart health, Dr Rahul Bhushan, Cardio Thoracic and Vascular Surgeon (Adult & Paediatric) at Apollo Hospitals Lucknow, shared his insights.
Ozempic Might Lower Heart Attack Risks, Doctor Explains
-1749818664682.jpg)
“The recent findings suggest Semglutide, also known as “Ozempic”, is widely known for its weight loss benefits, and has now shown effects that go beyond the weighing scale. It is showing improved blood sugar control, reducing blood pressure modestly, and has favorable effects on cholesterol profiles—all of which are major risk factors for heart disease.”, said Dr Bhushan.
Moreover, the data found in the Yale School of Medicine Research suggests Ozempic reduces systemic inflammation, which plays a key role in the development of atherosclerosis (a disease known to cause plaque, buildup of fats, cholesterol, and other substances causing hardening and narrowing of arteries) and cardiac events. So its cardiovascular benefits are both direct and indirect.
Evidence Supporting Ozempic for Heart
Ever since the 2017 wave of semaglutide being approved by the FDA in the form of Ozempic or Wegovy to help people struggling with type-2 diabetes caused a global talk. While this medicine did lower type-2 diabetes, it is now showing promising results for cardiovascular health in research studies like SELECT by Novo Nordisk, proving its effectiveness in patients with cardiology deficits, even without diabetes.
According to Dr Bhushan, “Clinical trials like SUSTAIN-6 and SELECT have shown that benefits start to show up relatively early, often within the first few months. These benefits go beyond sugar control—patients administered with this drug had fewer heart attacks, strokes, and other major events, even if they didn’t have diabetes. So, yes, the protective effect can begin quite early. As early as 6 months.”
ALSO READ: https://www.onlymyhealth.com/what-is-ozempic-teeth-side-effect-of-weight-loss-drug-12977832204
Who Stands to Gain the Most?
Although semaglutide is primarily prescribed for those with type 2 diabetes or obesity, experts believe its benefits may extend to a wider group of individuals, particularly those with a family history of heart disease, elevated cholesterol, or high blood pressure.
However, Dr. Bhushan cautions that not every patient is a candidate. “Ozempic is a prescription medication and should not be seen as a one-size-fits-all solution. Cardiovascular patients must consult their doctors before making any decisions,” he said.
How Does It Work?
Semaglutide mimics the action of GLP-1 (glucagon-like peptide-1), a hormone that plays a key role in:
- Enhancing insulin secretion
- Slowing down digestion
- Reducing appetite
- Improving lipid profiles
-1749818735425.jpg)
In doing so, it not only controls blood sugar but also lowers body weight, reduces inflammatory markers, and improves vascular function. All of these changes contribute to reduced strain on the heart and lower chances of blockages or clot formation.
ALSO READ: https://www.onlymyhealth.com/is-ozempic-effectiveness-for-pcos-12977832771
Comparing Semaglutide with Traditional Cardiac Therapies
While statins, ACE inhibitors, and beta-blockers remain the cornerstone of heart disease treatment, semaglutide is emerging as a new and valuable addition, especially in cases where metabolic syndrome plays a central role.
Some experts even argue that semaglutide may outperform lifestyle interventions alone in high-risk populations when it comes to preventing secondary heart attacks or strokes.
Potential Risks and Considerations
Like any medication, semaglutide is not without side effects. Common issues include:
- Nausea
- Vomiting
- Digestive discomfort
- Rarely, pancreatitis
Patients with a history of thyroid tumors or pancreatic conditions are typically advised to avoid the drug. Advised Dr Bhushan.
Dr. Bhushan recommends regular monitoring. “Doctors should closely monitor patients for side effects and adjust dosage as necessary. Informed prescription is key, he adds.
The Road Ahead: Will Ozempic Join Heart Disease Protocols?
With increasing evidence of its benefits, medical professionals are now considering whether semaglutide should be included in standard cardiovascular prevention protocols, even for patients without diabetes.
As per Dr. Bhushan, “For now, it is important to choose the right patients and keep a close eye on them as well as their diet, lifestyle, and regular monitoring.”
More studies are expected to further explore its role in non-diabetic populations, and regulatory agencies, as well as doctors and researchers alike, are watching closely for a breakthrough.
Final Thoughts
Semaglutide’s rise from a diabetes drug to a potential cardiovascular protector marks a major shift in preventive medicine. While more research is needed, the current data is promising and hopeful for struggling patients. For people living with diabetes, obesity, or multiple heart risk factors, Semaglutide may offer more than just weight loss; it could be a life-saving medicine.
Disclaimer: This article is for educational purposes only. Please consult a registered medical professional before starting or altering any medication.