Pallister-Hall syndrome refers to a disorder that affects the development of different parts of the body. Most people who have this condition tend to have extra fingers and toes and their skin between the fingers or toes tends to be more fused together. One of the characteristics of this disorder includes an abnormal growth in the brain called a hypothalamic hamartoma.
In most cases, the growth does not really lead to a medical condition, however, some hypothalamic hamartomas tend to cause seizures and hormone abnormalities that can be life-threatening at the time of infancy. Some other features of the Pallister-Hall syndrome include malformation of the airway, which is called a bifid epiglottis, obstruction of the anal opening and abnormalities in the functioning of the kidneys. Even though the signs and symptoms of this disease vary from mild to severe, only a small percentage of those affected tend to suffer from serious complications.
Pallister-Hall syndrome is a very rare condition, the prevalence of which is unknown.
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