Your healthcare provider can diagnose cutaneous mastocytosis by the appearance of your skin and confirm it by finding an abnormally high number of mast cells on a skin biopsy. The diagnosis of systemic mastocytosis is made when an increased number of abnormal mast cells is found during an examination of your bone marrow.
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Other tests that are important in evaluating a suspected case of mastocytosis include
- Measurement of a protein (tryptase) from mast cells in your blood
- A search for specific genetic mutations that health experts associate with this disease
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