Scientists Discover A Vitamin That May Aid Non-Alcoholic Fatty Liver Disease

Taking vitamin B12 and folate supplements can improve condition of non-alcoholic fatty liver disease patients.

Chanchal Sengar
Written by: Chanchal SengarPublished at: Aug 22, 2022Updated at: Aug 22, 2022
Scientists Discover A Vitamin That May Aid Non-Alcoholic Fatty Liver Disease

Non-alcoholic liver disease is one of the most common liver conditions in India with 10 million cases being diagnosed yearly. While liver diseases are majorly associated with alcoholism, non-alcoholic fatty liver disease is seen in people who consume little or no alcohol. There is fat accumulation around the liver leading to fatty liver. NAFLD causes inflammation and pain which can be really discomforting. Scientists have found a vitamin that may help in controlling inflammation, thereby managing NAFLD. 

If you are diagnosed with non-alcoholic fatty liver disease, you need to watch out for your diet. Since there is no standard treatment for this liver condition, management is the only option. Scientists from Duke-NUS Medical School in Singapore researched vitamins for fatty liver disease. As per the study published in the Journal of Hepatology, vitamin B12 and folate can help in controlling and lowering inflammation and scarring in patients of NAFLD. The team of researchers found that B12 and folate supplementation reduced scarring and inflammation of the liver in alcoholic liver disease patients. In addition to this, taking these supplements also slowed the progression of the disease. A statement by one of the researchers reads, "Our findings are both exciting and important because they suggest that a relatively inexpensive therapy, vitamin B12 and folic acid, could be used to prevent and/or delay the progression of NASH." 

How do vitamin supplements aid fatty liver disease?

Vitamin for Non-Alcoholic Fatty Liver Disease

Non-alcoholic fatty liver disease is caused due to fat buildup in the liver in non-alcoholic people. As this disease progresses, the healthy liver cells become scarred and get replaced by scarred tissues. Inflammation of the liver worsens scarring and increases the risk of severe complications. Scientists also found that NAFLD is caused due to degradation of syntaxin 17 protein. This causes scarred tissues to remain in the liver. Syntaxin 17 is a protein that helps in the digestion of fat. When it doesn’t synthesize properly, it causes inflammation and affects liver functions.

Vitamin B12 and folate increase Syntaxin 17 levels which reverse inflammation and scarring. Thus, taking vitamin B12 and folate supplements as well as adding foods with high vitamin B12 and folate is great for non-alcoholic fatty liver disease.