Treatment for MODY depends on the form of MODY you have such as MODY 2, which can be usually managed with exercise and diet and rarely drug or insulin therapy is needed. As MODY is a life-long disease, lifelong commitment to the following treatments is needed to keep blood sugar in control:
Lifestyle changes in MODY: This is an important aspect in the management of MODY like type 2 diabetes. Lifestyle changes recommended to control blood sugar levels include:
If lifestyle changes do not maintain your blood sugar in the target range, medications will be needed, but medications should not be used instead of lifestyle modifications. Use your medication along with lifestyle modifications.
Medications to treat MODY
Sulfonylureas: These drugs are usually given to patients with MODY, who need medications. Thesulfonylureas (such as glipizideand glyburide) are taken orally and stimulate the pancreas to secrete more insulin.
Insulin for MODY: Some patients with MODY 1 and 3 (approximately 30-40%) may need insulin eventually to control their blood sugar levels. Insulin is given as an injection if oral preparations of insulin are not available. Many different types of injectable insulin are available. These include:
Your doctor will prescribe the dose and type of insulin (short and long acting) to be taken based on your blood sugar control. Insulin injections can be taken as a standard injection or in other ways such as insulin pen, insulin infuser, jet injectors, insulin auto injector or insulin pump.
Patients with MODY 5 (a rare type of MODY) may require several different treatments as other organs apart from pancreas may be affected.