The number of COVID-19 cases have decreased in India and there is a slight improvement than a few months ago. However, new Covid mutations are making it difficult for the experts to find out more about this deadly virus. Coronavirus mutates and grows like any other virus, sometimes increasing the severity of this disease. Now, the Delta variant of COVID-19 was considered as the main factor behind the spread of infections in the dangerous second wave of Covid in India. And, this delta variant has now further mutated to 'Delta plus' or 'AY.1' variant.
The new Delta plus variant has been formed because of a mutation in the Delta or B.1.617.2 variant. At first, this variant was identified in India could have been a major cause behind the deadly second wave. Although, there is no evidence or research about the severity of the disease because of the new variant, but Delta plus is resistant to the monoclonal antibody cocktail treatment for COVID-19, which was recently authorised in India. Vinod Scaria, clinician and scientist at Delhi’s CSIR-Institute of Genomics and Integrative Biology (IGIB) said that the mutation is in the spike protein of SARS-COV-2, which makes the virus enter and infect the human cells. In the recent report of Public health England, on Coronavirus variants, the agency said that Delta plus was present in six genomes from India as of June 7. The health agency has now identified and confirmed a total of 63 genomes of the Delta variant with the new K417N mutation.
As per the reports, it was found in the initial data that Delta plus Covid variant indicates the signs of resistance in the monoclonal antibody cocktail treatment. Monoclonal antibody cocktail treatment for COVID-19 was certified by the Central Drugs Standard Control Organisation (CDSCO) recently. But, the severity of this infection is not known yet. The experts say that there is no need for immediate action or concern in India as the new COVID variant's growth in the country is still at a low level.
Points to remember:
- The new Delta plus variant has formed because of a mutation in the Delta
- The severity of the disease in this variant is unknown but experts say there is no cause of concern
- It has resistance against the monoclonal antibody cocktail treatment.
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