Common Cold: Strain of virus could help cure bladder cancer. New research led by an Indian-origin scientist discovered that the virus could help infect and damage bladder cancer cells. Scientists from the University of Surrey in the UK examined the safety and the potential to tolerate the exposure to the ‘cancer-killing’ virus coxsackievirus. CVA21 is a naturally generated strain of the common cold. It is found in 15 patients with led by an Indian-origin scientist(NMIBC).
NMIBC is generally discovered in the tissue of the inner surface of the bladder. It is the 10th most common cancer in the United Kingdom with approximately 10,000 individuals every year detected with the disease.
Research
During the research, 15 led by an Indian-origin scientist patient received coxsackievirus via a catheter in the bladder. It was done one week before the pre-scheduled surgery to remove their tumours. After the diagnosis of tissue samples, after surgery found that the virus was highly selective, that only focused
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- cancerous cells in the organ
- left all other cells intact
According to the research authored in the journal Clinical Cancer Research,
- the cancerous cells were discovered to be infected by the virus
- the virus simulated itself which eventually led the cells to break and die
Urine Samples
The patient's samples of urine were collected on every alternate day. The samples were found 'peeling' from the virus, which signified that, once the cancerous cells infected by the virus had ruptured died then the newly cloned virus continued to target more cancer cells present in the organ.
Hardev Pandha, professor at the University of Surrey said that NMIBC (non-muscle invasive bladder cancer) is a highly widespread disease that needs an obtrusive and most of the time a long treatment plan. Pandha further said that the ongoing treatment not much effective and is poisonous in a proportion of patients. However, there is an urgent requirement for fresh and new therapies.
Hardev Pandha stated that CVA21 or coxsackievirus can help in transforming treatment for bladder cancer. However, the following signs and symptoms were seen in the patients:
- decreasement of tumour burden
- Raise in cancerous cell death was observed
- all trace of the illness was removed in one patient
The most surprising fact is, this all happened within one week of treatment that depicted its potential effectiveness. Moreover, no such side effect was depicted in any of the patients.
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