What are the types of Pelizaeus Merzbacher Disease?

By  ,  National Institute of Health
Jul 14, 2011

There are four general classifications within this spectrum of diseases. In order of severity, they are:

  • Connatal PMD, which is the most severe type and involves delayed mental and physical development and severe neurological symptoms;
  • Classic PMD, in which the early symptoms include muscle weakness, involuntary movements of the eyes (nystagmus), and delays in motor development within the first year of life;
  • Complicated SPG2, which features motor development issues and brain involvement, and,
  • Pure SPG2, which includes cases of PMD that do not have neurologic complications.

Noticeable changes in the extent of myelination can be detected by MRI analyses of the brain. Additional symptoms of PMD may include slow growth, tremor, failure to develop normal control of head movement, and deteriorating speech and mental function.

 

 

Loading...
Is it Helpful Article?YES10782 Views 0 Comment
I have read the Privacy Policy and the Terms and Conditions. I provide my consent for my data to be processed for the purposes as described and receive communications for service related information.
This website uses cookie or similar technologies, to enhance your browsing experience and provide personalised recommendations. By continuing to use our website, you agree to our Privacy Policy and Cookie Policy. OK