Chronic lymphocytic leukaemia (CLL) is the most common type of leukaemia in adults over 60, accounting for nearly a third of leukaemia cases in Western countries. In India, however, its prevalence is lower (5–6%). This slow-growing cancer affects lymphocytes, a type of white blood cell that fights infections. Symptoms like fatigue, frequent infections, swollen lymph nodes, and unexplained weight loss often appear gradually—or not at all. Many patients are diagnosed accidentally during routine blood tests. While the word ‘cancer’ can be frightening, CLL often progresses so slowly that immediate treatment isn’t always necessary. But can patients live normally after treatment? Let’s explore what life with CLL looks like today.
Oncologist Explains Chronic lymphocytic leukaemia (CLL)![1 - 2025-04-11T141500.597]( "Chronic lymphocytic leukaemia (CLL)")
Dr Aditya Sarin, Associate Consultant, Medical Oncology, Sir Ganga Ram Hospital, Delhi, explains, “CLL disrupts lymphocytes, weakening the immune system over time. However, many patients live for years without symptoms.”
Key Facts About CLL
- Age Factor: Primarily affects adults over 60, but younger adults can develop it.
- Symptoms: Fatigue, swollen lymph nodes (neck/armpits), frequent infections, night sweats, and unexplained weight loss.
- Diagnosis: Often detected through routine blood tests showing high lymphocyte counts.
To Treat or Wait? The CLL Approach
“In early stages, we often don’t treat CLL immediately,” says Dr Sarin. Instead, doctors use ‘watchful waiting’ to monitor progression. Treatment begins only when symptoms worsen or blood counts drop dangerously.
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When Is Treatment Needed?![3 (57)]( "Chronic lymphocytic leukaemia (CLL) treatment")
-1744361403473.jpg "Chronic lymphocytic leukaemia (CLL) treatment")
- When treatment becomes necessary, modern therapies like BTK inhibitors (e.g., ibrutinib) and BCL2 inhibitors (e.g., venetoclax) have revolutionised CLL care.
- Chronic lymphocytic leukaemia (CLL) explained: Can patients live normally? An oncologist reveals how modern treatments help.
- Dr Sarin shares, “These drugs target cancer cells without harming healthy ones. Studies show 5-year survival rates exceed 90%, with many patients living 10–20 years post-diagnosis.”
Can You Live Normally with CLL?![2 - 2025-04-11T141459.118]( "Chronic lymphocytic leukaemia (CLL) treatment")
The short answer: Yes. Dr Sarin states, “Some patients live healthy lives without any treatment at all, while those undergoing therapy also enjoy productive lives.”
Tips for Maintaining a Healthy Life Post-Treatment:
- Follow your doctor’s advice on regular check-ups and medications.
- Maintain a balanced diet rich in fruits, vegetables, and whole grains.
- Stay active with light exercises to boost overall health and immunity.
- Manage stress through practices like meditation or yoga.
Life During/After Treatment
- Most therapies are oral (pill-based), allowing home treatment.
- Side effects like mild fatigue or bruising are manageable.
- Many patients return to routine activities within weeks.
Keys to Thriving with CLL
- Stay Proactive: Attend all follow-ups to catch changes early.
- Boost Immunity: Prioritize sleep, nutrition, and stress management.
- Avoid Myths: “Not all CLL needs treatment—trust your care plan,” advises the expert
Conclusion
Chronic lymphocytic leukaemia may sound intimidating, but it’s a highly manageable condition with today’s medical advancements. Early detection and effective treatments allow patients to lead fulfilling lives despite the diagnosis. Dr Aditya Sarin encourages those diagnosed to consult their oncologist promptly for personalised care plans. With proper treatment and lifestyle adjustments, life after CLL can indeed be normal and rewarding.