NMN (Nicotinamide mononucleotide) is a naturally-occurring molecule derived from niacin (Vitamin B3) that plays a vital role in powering your energy and vitality at a cellular level. In the last few years, NMN has generated a ton of buzz for its potentially enormous anti-aging benefits. That’s why we’re here to review the best NMN supplements to support longevity for you.
A nucleotide found in many plants and animals, NMN acts as a biological precursor to another essential molecule known as NAD+ (Nicotinamide Adenine Dinucleotide).
Adequate NAD+ levels are crucial for aiding in:
- Fueling Abundant Energy
- Repairing Damaged DNA
- Powering Cellular Wellness
- Supporting Gene Expression
Inside the human body, several chemical reactions naturally convert NMN into usable NAD+. Your cells must have sufficient NMN intake to achieve optimal NAD+ levels. However, both our internal NMN and NAD+ levels decline steeply with age.
Each molecule can be found in trace amounts in some foods. However, when ingested orally, NAD+ is extremely difficult for the human body to absorb properly. And small amounts are unlikely to have much effect on your health and wellness anyways.
Therefore, the use of NMN supplementation to enhance NAD+ levels and ultimately reduce adverse aging outcomes has been gaining research support and popularity among anti-aging experts.
If you’re interested in aging well physically and mentally, NMN and the NAD+ it helps to synthesize could be pivotal to your success. With that in mind, we’ll dive into the best NMN supplements available right now.
Best NMN Supplements—The Top 4
After examining the market for high-quality NMN supplements, we’ve settled on 4 elite all-natural products that could help you to optimize NAD+ levels.
We took into account factors like NMN quality, manufacturing practices, ancillary ingredients, reported safety policies, affordability, and some others to determine which are the best NMN supplements.
Our consensus top 4 NMN supplements are:
- #1 GenF20 Liposomal NMN+—Best Overall Supplement
- #2 Double Wood NMN—Best For Energy Metabolism
- #3 Cymbiotika NMN—Best For Weight Loss Support
- #4 Youth & Earth NMN—Best For European-Based Users
GenF20 Liposomal NMN+ takes the #1 spot on our list of the best NMN supplements. This all-natural supplement is constructed with elite ingredients and promotes enhanced bioavailability for its NMN. These factors, along with the supplement’s track record of success, make it our clear-cut best NMN supplement.
That said, we’ll take a closer look at each of these reliable NMN supplements to help you understand exactly how they work. But first, we’ll quickly highlight the potential effects NMN supplementation could have for you.
Why You Should Use The Best NMN Supplements
Simply put, every cell in your body operates less efficiently as NAD+ levels decline. And all of us will experience a progressive degradation in NAD+ as we age.
Data from a clinical study performed by researchers associated with the University of Minnesota suggests that NAD+ levels decline significantly after our early 20s, resulting in a plethora of detrimental aging outcomes over time.
However, there is good news.
A clinical review published in Integrative Medicine: A Clinician’s Journal stated, “Taken orally, NMN is rapidly absorbed and converted to NAD+.”
While another study involving researchers from the Netherlands, Singapore, and India concluded a group of healthy middle-aged adults supplementing with NMN showed higher blood NAD+ concentrations after 30 days.
NMN supplementation helps to support:
- Enhanced Cognition
- Elevated Blood Flow
- Improved Metabolic Efficiency
- Better Body Composition
- Strengthened Stamina
- Daily Energy Gains
- Greater Focus
If you feel “Father Time” catching up to you mentally or physically, supplementing with a high-quality NMN supplement could help you to feel, look, and think younger again.
Now, it’s time to put the best NMN supplements under the microscope.
#1 GenF20 Liposomal NMN+—Best Overall Supplement
GenF20 Liposomal NMN+ delivers highly pure NMN molecules with impressive bioavailability, making it the best NMN supplement on the market.
For several years now, this all-natural formula has been helping men and women in their 30s, 40s, 50s, 60s, 70s, and beyond recapture a significant portion of their youthful spark.
Typical benefits of GenF20 Liposomal NMN+ may include:
- Revamped Mindset
- Greater Physical Fitness Results
- More Day To Day Energy
- Improved Ability To Focus
- Reduced Skin Imperfections
- Enhanced Sleep Quality
- Growing Libido
As you see, GenF20 Liposomal NMN+ could bring a lot to the table to help you in the continuous struggle against aging.
Some users may experience noticeable increases in energy and sleep quality after just a few weeks of daily use. However, the average supplement response time (when you’re likely to see tangible results) should be approximately 4-6 weeks.
As with all the supplements on this list, you’ll need to continue using GenF20 Liposomal NMN+ continuously to achieve progressive improvements. If you stop using the supplement, the benefits will subside in time.
Ingredient Overview
GenF20 Liposomal NMN+ incorporates some of the highest quality NMN molecules you’ll find anywhere.
Each serving contains 98% β-Nicotinamide Mononucleotide (NMN). When you order from the official manufacturer’s webpage, they’ll provide third-party tested documentation to prove that claim.
As great as the NMN quality is in this supplement, the real revolutionary breakthrough factor lies in the “Liposomal” aspects. That’s because the NMN in GenF20 Liposomal NMN+ utilizes liposomes, or tiny spherical structures, composed of lipids that protect the NMN while it’s in your digestive tract.
The problem with NMN in general is that it’s not well-absorbed in the human body. Our stomach acids quite literally attack and break these precious molecules apart, resulting in low bioavailability.
However, GenF20 has “cracked the code,” if you will, by encasing its high-quality 98% pure NMN in liposomes that can significantly enhance the stability and bioavailability of the molecules inside.
This formula should yield the greatest bioavailable NMN of any supplement around.
And the ingredient list is:
- Organic
- Non-GMO
- Gluten-Free
- Soy-Free
- Egg-Free
- Dairy-Free
- Sugar-Free
- Preservative-Free
GenF20 Liposomal NMN+ uses high-quality NMN with a proprietary bioavailability enhancement system and comes with no known negative side effects. These features should set users up for sustainable success in reducing signs of aging.
Primary Characteristics
There’s a lot to like about GenF20 Liposomal NMN+. It’s loaded with positive attributes that set it apart from the field.
Key attributes include:
Contains Pure 98% NMN
The NMN molecules in this supplement are incredibly high-quality. They’re harvested from organic sources and purified through a patented process that results in a premium finished product.
Many NMN supplements attempt to cut costs by using lower-quality NMN. However, that’s certainly not a concern here.
You can rest assured knowing each serving of GenF20 Liposomal NMN+ provides a clean form of NMN that can help to yield massive anti-aging results.
Liposomal Protection For Maximum Absorption
The liposomes, or fat-based layered vesicles, that protect the NMN molecules in GenF20 Liposomal NMN+ could significantly enhance the rate at which your body absorbs the NMN.
As a result, it’s likely that you’ll be able to achieve more efficient anti-aging results due to the enhanced bioavailability.
This feature takes a good all-natural NMN supplement and makes it genuinely elite. Liposomal delivery systems are usually only found in high-end supplements, vitamins, and therapeutics.
Excellent Ease Of Use
GenF20 Liposomal NMN+ is incredibly easy to use. It requires users to take just a single small capsule per day.
It’s best to take that capsule around the same time every day for consistency. And it’s recommended to take each capsule with a glass of water.
With 1 capsule per day, you may begin to notice substantial gains in energy and vitality within a few weeks. Of course, there should be no ill effects (no reported negative side effects) related to GenF20 Liposomal NMN+.
GenF20 is a health supplement brand with many years of experience building several first-class health products. So, it comes as no surprise that GenF20 Liposomal NMN+ is made with such quality craftsmanship.
Manufacturing Practices
GenF20 Liposomal NMN+ uses some of the strictest, safest manufacturing practices in the industry. You can feel comfortable knowing that each and every batch will be consistent and free of contaminants.
That’s because GenF20 Liposomal NMN+ is manufactured in cGMP facilities adhering to regulations set forth by the FDA.
And it’s made in the USA.
Money-Back Guarantee
GenF20 Liposomal NMN+ comes with an elite money-back guarantee.
You can order your supplement, open it, use it, and return it up to 67 days later to get a refund of the purchase price.
This is a great reassurance for users and shows the utmost confidence on the manufacturer’s end.
Price & How To Buy
A bottle containing a 2-month supply of GenF20 Liposomal NMN+ costs $69.95. When you buy in bulk, you’ll get significant savings.
For instance:
- 3 Bottles (6-Month Supply)—$66.65 Per Bottle
- 6 Bottles (12-Month Supply)—$58.33 Per Bottle
Payment installations are available. And all purchases are protected by the 67-day money-back guarantee.
It’s best to purchase through the official GenF20 Liposomal NMN+ website to get the best price, excellent customer service, and the money-back guarantee.
They also offer free shipping within the continental USA.
#2 Double Wood NMN—Best For Energy Metabolism
Next up on our list of the best NMN supplements is Double Wood NMN. Another American-made supplement, Double Wood NMN, uses a quality form of NMN to help boost energy metabolism.
Double Wood NMN has earned a reputation for reliable results and has helped many people to feel more alert and focused when they once may have been crashing.
Typical benefits of Double Wood NMN may include:
- Greater Daily Energy
- Reduced Afternoon Fatigue
- Boosted Sleep Quality
- Enhanced Moods
- Reduced Irritability
With just 2 capsules a day, Double Wood NMN can aid in supporting many aspects of wellness that may deteriorate due to age.
On average, users can expect to notice at least some of these benefits in 4-6 weeks. However, like all health supplements, the response time will vary from person to person. Some may experience enhancements sooner, while others may be on the longer end of the time spectrum.
It’s important to be patient and remain consistent with usage.
Ingredient Overview
Double Wood NMN contains good quality NMN, along with some additional ingredients that support the NMN molecule’s structure and delivery.
Other ingredients include:
- Gelatin
- Organic Rice Flour
These are the ingredients making up the NMN encapsulation material. They may help to offer some limited protection to the NMN once it enters your system.
Overall the Double Wood NMN formula is:
- Non-GMO
- Gluten-Free
- Soy-Free
Double Wood NMN contains adequate NMN molecules, extracted naturally, to provide some solid anti-aging benefits. All and all, it deserves to be considered among the best NMN supplements.
Primary Characteristics
There are a couple of reasons to suggest Double Wood NMN may help users to mitigate some of the common pitfalls of aging. We like the simple reliability of this supplement.
Key attributes include:
Good NMN Molecule Quality
Double Wood NMN delivers a dependable serving of NMN in every capsule. It could help to support healthy aging and significantly boost energy metabolism.
The NMN molecules in Double Wood NMN are reportedly extracted and synthesized from natural Non-GMO sources. And a third-party test suggests there are no known negative side effects.
Made In The USA
Double Wood NMN is manufactured and distributed in the United States of America. With an American-made supplement, there’s an expectation for dependable, safe production standards.
Generally speaking, the best NMN supplements are manufactured in the USA, where cutting-edge manufacturing processes are utilized.
Double Wood NMN is still a relatively new NMN product, but the early returns suggest it’s a quality supplement.
Manufacturing Practices
As mentioned, Double Wood NMN is made in the USA. It’s also constructed in cGMP facilities, adhering to safety regulations written by the FDA.
These practices suggest reliability and elite supplement performance.
Money-Back Guarantee
Double Wood NMN comes with a good money-back guarantee.
You can return your product up to 30 days after receiving it. That means you can try it and get a refund of the purchase price if it doesn't help you within the allotted time frame.
Price & How To Buy
A bottle (1-month supply) of Double Wood NMN costs $48.95. If you subscribe for recurring purchases, you’ll pay $43.08.
And buying in bulk can save some money.
For instance:
- 2 Bottles (2-Month Supply)—$46.48 Per Bottle
- 3 Bottles (3-Month Supply)—$42.65 Per Bottle
Subscribing to recurring purchases saves 12% on all orders.
You’ll want to buy directly from the Double Wood NMN official homepage.
#3 Cymbiotika NMN—Best For Weight Loss Support
Third among the best NMN supplements is Cymbiotika NMN, a quality NMN supplement hailing from the USA.
Cymbiotika NMN uses a potent NMN source in combination with several additional ingredients that may help support further anti-aging and weight loss.
Typical benefits of Cymbiotika NMN may include:
- Increased Metabolic Efficiency
- Greater Weight Loss
- Improved Energy
- Boosted Physical Fitness
- Motivation Gains
By taking 2 capsules a day, Cymbiotika could support these benefits and contribute to overall anti-aging benefits in approximately 4-6 weeks.
Ingredient Overview
Cymbiotika NMN employs a good quality NMN to help users achieve results.
However, the real unique feature of this supplement relates to the ancillary ingredients, which support improved health and wellness.
Other ingredients include:
- Apigenin
- Green Tea Extract
- Resveratrol
- Green Coffee Bean
Resveratrol is a polyphenol found in some fruits. It acts like an antioxidant and helps to reduce inflammation. At the same time, green coffee beans could help to fuel fat-burning and support daily energy.
Overall Cymbiotika NMN is:
- Gluten-Free
- Soy-Free
- Sugar-Free
- Vegan
- Keto
Cymbiotika could be a great NMN option, especially for individuals who would like some added potential fat-burning ingredients.
Primary Characteristics
Cymbiotika NMN uses a highly-unique formulation to provide NMN and additional support.
There are several characteristics that put this product in the conversation of the best NMN supplements.
Key attributes include:
The Presence Of Resveratrol
A compound found in grapes, as well as some berries and nuts, resveratrol can help to reduce inflammation and oxidative stress.
It’s also believed to help with blood flow and stimulate weight loss.
Use Of Green Coffee Bean & Green Tea Extract
Both green coffee beans and green tea extract can contribute elements of fat-burning, enhanced stamina, and potentially improved cognition.
Adding these components to go with NMN may help support some added wellness benefits.
We should note that green coffee beans do attach some caffeine to the formulation.
Cymbiotika NMN is a dynamic NMN supplement that is ideal for those struggling with pesky body fat. Incorporating this supplement into one’s life could help improve the overall quality of life.
Manufacturing Practices
Cymbiotika NMN is manufactured in cGMP facilities in the USA.
Again, as with most of the best NMN supplements, being American-made in reportedly safe facilities is a considerable indication of quality.
Money-Back Guarantee
Cymbitokia NMN offers a 30-day money-back guarantee but won’t refund any opened or used packaging.
So, unfortunately, you won’t be able to use the supplement to see how it works for you beforehand.
Price & How To Buy
A bottle (1-month supply) of Cymbiotika NMN costs $77.00. However, when you subscribe for recurring purchases, you’ll pay $69.30.
If you subscribe, you’ll save more on bulk orders, too.
Go to the official Cymbiotkia NMN homepage to learn more.
#4 Youth & Earth NMN—Best For European-Based Users
The fourth and final of the best NMN supplements is Youth & Earth NMN.
Manufactured primarily in the UK, Youth & Earth could represent a reliable, affordable option for European-based users.
Typical Benefits of Youth & Earth NMN may include:
- More Optimistic Mindset
- Improved Stamina
- Boosted Libido
- Metabolic Enhancements
- Reduced Body Fat
Youth & Earth should promote multiple positive benefits to diminish age-related deterioration.
Multiple wellness enhancements can manifest within 4-6 weeks of daily use. However, significant improvements may appear later.
Ingredient Overview
Youth & Earth NMN provides highly-purified NMN molecules naturally extracted from clean sources.
The capsules containing the NMN are designed to be “gastro-resistant” to help ensure greater NMN bioavailability in the digestive tract.
Youth & Earth NMN is:
- Non-GMO
- Soy-Free
- Gluten-Free
- Vegan-Friendly
Youth & Earth NMN requires users to ingest 2 small capsules daily. And it has no known negative side effects. The 100% natural formulation could help you to feel younger and more vibrant over time.
Primary Characteristics
There are several elements to like about Youth & Earth NMN. We believe it’s one of the best NMN supplements, especially for European-based users.
High-Quality NMN Molecules
The NMN used in Youth & Earth NMN is third-party tested and reported to be high-quality. This should help to yield more efficient anti-aging results.
Anytime you look at an NMN supplement, the NMN quality is paramount to success.
UK-Based Manufacturer
Youth & Earth NMN is based in the United Kingdom and according to their website they provide “Brexit tariff-free” orders within the EU.
Shipping times and shipping costs could be significantly lower for European-based users.
If you’re living in Europe and would like to try one of the best NMN supplements, Youth & Earth NMN may be your best bet.
Manufacturing Practices
As you know, Youth & Earth NMN is primarily manufactured in the UK.
That said, the manufacturer reports adhering to cGMP guidelines, suggesting it’s safely manufactured.
UK-based supplement manufacturers have a solid reputation for quality. Shipping fees, as well as shipping time, within the UK (and most of Europe), are affordable and quick.
Money-Back Guarantee
Youth & Earth NMN provides a 60-day money-back guarantee but won’t refund any used packaging.
Therefore, there’s no free trial while using this supplement.
Price & How To Buy
A bottle (1-month supply) of Youth & Earth NMN costs $51.41.
You’ll only receive savings on bulk orders when you sign up for the Youth & Earth subscription service with recurring buys.
Go to the official Youth & Earth website to get the best overall experience.
Best NMN Supplements—Final Thoughts
Mounting evidence suggests NMN supplementation could be the ideal way to support naturally increased NAD+ levels and reduce adverse aging outcomes.
Using the best NMN supplements should help users “age like a fine wine” and thoroughly enjoy life for many years to come.
If you’re serious about maintaining or building a high quality of life, the best NMN supplements can help you.