What are the causes of Osteogenesis Imperfecta and Constipation?

By  ,  National Institute of Health
Jul 11, 2011

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Constipation can be caused by inadequate dietary fiber, lack of exercise, and dehydration. Colon obstruction and illness are additional causes. Some medications, especially painkillers, can cause constipation because they decrease the normal motion and movement of the bowel. Adults with OI and parents of children with OI are encouraged to check with their doctor or pharmacist about side effects and possible drug interactions from their medicines and dietary supplements.


OI may contribute to constipation, especially in people with the short stature and pelvic malformation associated with OI Type III. The colon and bowel may be prevented from functioning normally if the hips and pelvis are narrow or malformed. A specific pelvic malformation, known as acetabular protrusion, can affect some people with OI Type III and cause a predisposition to constipation. Diminished mobility and low levels of physical activity also contribute to constipation.


Dehydration is a well-known factor contributing to constipation. Children with OI who have increased perspiration should be closely monitored so they remain hydrated.



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