What Is The Impact of Thalassaemia on Fertility In Women ?

By Vanshika Gaur
08 May 2025, 11:00 IST

Thalassaemia refers to a blood disorder where the body is unable to produce enough haemoglobin, which can lead to Anaemia. However, thalassaemia can also impact fertility, especially in women. Tap to know how!

Irregular Periods

Thalaessaemia can cause irregular periods in women due to hormonal imbalances, which can also affect puberty.

Chronic Illness

This blood disorder can also be caused due to chronic illness, impacting overall health. This condition can potentially cause fatigue and affect reproductive health.

PCOS

This condition can increase the risk of Polycystic Ovary Syndrome (PCOS), which can result in hormonal imbalance and irregular periods.

Oxidative Stress

The free radicals and toxins in the body can damage the tissues in the reproductive system, potentially reducing fertility.

Iron Overload

Individuals with thalassaemia often require frequent blood transfusions, leading to iron overload, affecting pituitary gland and hypothalamus impacting reproductive hormones.

Affects Immune System

Thalassaemia can also affect the immune system, which can sometimes interfere with the fertilisation process.

Information Credits

According to PubMed, thalassaemia-induced infertility is mainly caused by iron deposition in the pituitary gland. It is advisable to consult a healthcare professional for personalised suggestions.