Prognosis of Peyronies Disease

By  , Expert Content
Feb 15, 2012

Peyronie's disease is a condition, which affects the penis. A plaque or scar tissue develops in the penis in this disorder. The plaque starts as an area of localised inflammation, which gradually progresses to form a hardened scar. The disease mostly affects middle  aged men (40 to 60 years old), but men of any age over adolescence can be affected.

Prognosis of Peyronies Disease

Symptoms of the Peyronies disease (such as pain, change in curvature of the penis) may appear suddenly or develop gradually and the severity of symptoms may vary from mild to severe.

In many cases, Peyronie’s disease is a self-limiting condition. The pain may improve and gradually disappear without treatment with time (in a few months). The bend of penis in men with Peyronie's disease gradually worsens in some cases and at some point, stops (occasionally, the curvature may improve without treatment). If the disease stabilizes and the man with Peyronie’s disease is able to have sexual intercourse,  surgical treatment is usually not necessary.

In some men with Peyronie's disease, the bend in the penis may be severe and it may make sexual intercourse difficult. This can disrupt a couple’s physical and emotional relationship and cause negative impact on a man’s self-esteem; these men will eventually require surgery.

Oral Medication Prognosis

Oral medication is often given as the first course of treatment. Medications, however, have been shown to have limited efficacy. Therefore, it is mostly considered for men with early or active Peyronie's disease.

Surgical Prognosis

Success of surgery for Peyronie’s disease is variable, however, it is usually the most successful treatment. In many cases, the penis may not become straight after surgery. Apart from this, some men may develop erectile dysfunction or even numbness of the penis following surgery. Hence, surgery is considered after much deliberation. Surgery to correct penile deformity is done in men with stable Peyronie's disease that has been present for at least a year and is not progressive. If surgery is attempted before the disease has stabilized, the condition can continue to progress after the operation has been performed.


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