How do People inherit Smith-Magenis Syndrome?

By  ,  Onlymyhealth editorial team
Jul 27, 2011
Quick Bites

  • Smith-Magenis syndrome affects several parts of the body.
  • The changes in facial featues may be subtle during childhood.
  • Smith-Magenis syndrome cannot be inherited.
  • It happens during the development of the fetus in the womb.


Smith-Magenis syndrome refers to a developmental disorder that affects several parts of the body. The most common characteristic of this disorder is a change in facial features which includes a broad, square-shaped face with full cheeks and a lower jaw that can be prominently visible. Other facial features include a mouth that is turned downward with an outward-curving upper lip. These unusual facial features may be subtle during childhood, though they tend to become distinctive later in childhood or adulthood. Dental abnormalities may also be seen in the patients.

Smith-Magenis Syndrome
Cognitively, these patients lack intellectual ability, have delayed speech and language skills. Apart from these they also experience sleep disturbances and behavioural problems.


Can this Disease be Inherited?

Smith-Magenis syndrome is not really inherited, implying that if the mother or father has it, the child is not quite pre-disposed to have it too. The condition usually results because of a genetic change that takes place at the time of the formation of reproductive cells or during the early development of the fetus. In most cases of this disease, the patient does not have a history of the condition in his/her family.


Read more articles on Smith-Magenis Syndrome.

Is it Helpful Article?YES10967 Views 0 Comment
I have read the Privacy Policy and the Terms and Conditions. I provide my consent for my data to be processed for the purposes as described and receive communications for service related information.
This website uses cookie or similar technologies, to enhance your browsing experience and provide personalised recommendations. By continuing to use our website, you agree to our Privacy Policy and Cookie Policy. OK