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Who is at risk from Zollinger Ellison Syndrome?

By  ,  Onlymyhealth editorial team
Jun 23, 2014
4.8 / 5(4 Ratings)
Quick Bites

  • The syndrome is a condition in which tumours from in pancreas.
  • These tumours release gastrin hormones.
  • The syndrome can lead to peptic ulcers in the stomach.
  • Pain in the abdomen and diarrhea are some of the symptoms.

More

What is Zollinger-Ellison syndrome?

Zollinger-Ellison syndrome is condition when one or more tumours are formed in the pancreas or in the upper part of small intestine. These tumours are called gastrinomas and they secrete gastrin hormone in large quantities which leads the stomach to produce acid. This acid formation causes peptic ulcers in the stomach. Although the disease rare it may take place at any age. People aged between 30 and 50 years are mostly diagnosed with syndrome.  

Zollinger Ellison Syndrome Risks

What are the Signs and Symptoms of Zollinger-Ellison syndrome?

The person suffering from the syndrome may experience the following symptoms:

  • Pain in the abdomen
  • Diarrhea
  • Burning sensation or aching in the upper part of the abdomen
  • Nausea followed by vomiting
  • Body weakness
  • Unusual weight loss
  • Decrease in appetite
  • Anemia

Zollinger Ellison Syndrome Risks

 

What Causes Zollinger-Ellison syndrome?

Although the exact cause of the condition is yet to be known but, the sequence in which the events occur are quite clear. At the beginning of the syndrome, a tumour occurs in the pancreas, duodenum, or in the lymph nodes placed adjacent to the pancreas.

The pancreas is responsible for producing enzymes which are required for digestion o food. Also, hormones like gastrin are produced by the pancreas which prevents the stomach from producing acids.

The tumour which occurs in the syndrome is made up of cells which secrete gastrin in large amounts causing the stomach to release acids which lead to peptic ulcers.

Image courtesy: Getty Images

Read more on Zollinger-Ellison syndrome.

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