There are four general classifications within this spectrum of diseases. In order of severity, they are:
Noticeable changes in the extent of myelination can be detected by MRI analyses of the brain. Additional symptoms of PMD may include slow growth, tremor, failure to develop normal control of head movement, and deteriorating speech and mental function.
Treatment for pelizaeus merzbacher disease is symptomatic and supportive and may include medication for movement disorders.read more
Patients suffering from Pelizaeus-Merzbacher disease usually die because of respiratory complications during their childhood.read more