There is currently no cure for OI. Treatment involves supportive therapy to decrease the number of fractures and disabilities, help with independent living and maintain overall health. OI is best managed by a medical team including the child's own doctor, and genetic, orthopedic and rehabilitation medicine. Supportive therapy is unique to each individual depending on the severity of their condition and their age.
Physical and occupational therapies to help improve their ability to move, to prevent fractures and to increase muscle strength are often useful.
Fractures are treated as they would be in children and adults who do not have OI. An orthopedic treatment called intramedullary rodding (placing rods in the bones) is used to help with positioning of legs that helps with more normal functioning when necessary.
A newer treatment with medication called biophosphonates is being used to help with bone formation and to decrease the need for surgery.
The majority of OI is caused by a single dominant mutation in one of two type I collagen genes: COL1A1 or COL1A2.read more
Treatment choices for Osteogenesis Imperfecta and Constipation include: diet and fluids, exercise and activity, certain home remedies and medications.read more