What is the treatment of Histoplasmosis?

By  ,  National Institute of Health
Jan 06, 2013

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How is OHS treated?


The only proven treatment for OHS is a form of laser surgery called photocoagulation. A small, powerful beam of light destroys the fragile, abnormal blood vessels, as well as a small amount of the overlying retinal tissue. Although the destruction of retinal tissue during the procedure can itself cause some loss of vision, this is done in the hope of protecting the fovea and preserving the finely-tuned vision it provides.

How effective is laser surgery?

Controlled clinical trials, sponsored by the National Eye Institute, have shown that photocoagulation can reduce future vision loss from OHS by more than half. The treatment is most effective when:

  • The CNV has not grown into the center of the fovea, where it can affect vision.
  • The eye care professional is able to identify and destroy the entire area of CNV.

Does laser surgery restore lost vision?

Laser photocoagulation usually does not restore lost vision. However, it does reduce the chance of further CNV growth and any resulting vision loss.

Does laser surgery cure OHS?

No. OHS cannot be cured. Once contracted, OHS remains a threat to a person's sight for their lifetime.


People with OHS who experience one bout of abnormal blood vessel growth may have recurrent CNV. Each recurrence can damage vision and may require additional laser therapy. It is crucial to detect and treat OHS as early as possible before it causes significant visual impairment.


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