What are the symptoms of Neuroleptic Malignant Syndrome?

By  ,  Onlymyhealth editorial team
Oct 10, 2012

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Quick Bites

  • Neuroleptic malignant syndrome is a neurological disorder.
  • Altered mental health is one of its characteristics.
  • Patients may have experience muscle rigidity.
  • The body temperature usually rises high.

Neuroleptic malignant syndrome is a neurological disorder which is characterised by the altered mental health, muscle rigidity hyperthermia and autonomic hyperactivity. The condition occurs as a result of adverse reaction to neuroleptic or antipsychotic drugs. The condition usually develops within the first few weeks of the treatment with drugs. However neuroleptic malignant syndrome may develop any time during the therapy period. It could also develop due to the anti-parkinsonism drugs.

Neuroleptic Malignant syndrome

Symptoms of Neuroleptic Malignant syndrome

Common symptoms of the condition include :

  • Hyperthermia
  • Autonomic hyperactivity
  • High fever
  • Sweating
  • Unstable blood pressure
  • Stupor
  • Muscular rigidity

Muscular rigidity


The causative drugs are stopped and complications are treated supportively in intensive care units. Fever is treated aggressively and muscle relaxants are advised. Apart from these steps, the doctor will advice dopaminergic drugs such as dopamine agonist.


Image Courtesy : Getty

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