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What is the Prognosis of Pelizaeus Merzbacher Disease?

By  ,  Onlymyhealth editorial team
Dec 05, 2014
4.8 / 5(4 Ratings)
Quick Bites

  • Pelizaeus-Merzbacher disease is an inherited condition.
  • The condition affects brain and spinal cord.
  • Impaired intellectual functions are caused.
  • Motor skills may also be hindered.

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What is Pelizaeus-Merzbacher Disease?

Pelizaeus-Merzbacher disease is a condition which is inherited and affects the brain and the spinal cord. The condition belongs to a group of genetic disorders called leukodystrophies. When an inability to form myelin is caused it leads to Pelizaeus-Merzbacher disease.

Pelizaeus-Merzbacher Disease

The condition leads to impaired intellectual functions, like language and memory and delayed motor skills like coordination and walking. The motor skills tend to be more severely affected than the intellectual functions.
The condition is usually categorized into classic and connatal types. Both the two types differ in severity and their features overlap.

 

Pelizaeus-Merzbacher Disease

Prognosis for Pelizaeus-Merzbacher Disease

The people who suffer from Pelizaeus-Merzbacher disease usually die of respiratory complications during childhood. However, if given proper care they can live up to the third decade of their life. Patients who suffer from classic Pelizaeus-Merzbacher disease can live into their fifth or sixth decade of their life. Patients who suffer from predominantly spastic paraplegia phenotype lead a normal life span and may even reproduce.

Image courtesy: Getty Images

Read more on Pelizaeus-Merzbacher Disease Diagnosis and Prognosis.

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