What is Holoprosencephaly?

By  ,  Onlymyhealth editorial team
Oct 28, 2014
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Quick Bites

  • Failure of embryonic forebrain leads to the disorder.
  • Facial deformities are caused by the disorder.
  • Disorder can lead to death in infants.
  • The treatment is completely symptomatic.

What is Holoprosencephaly?

Holoprosencephaly is a condition caused by the failure of embryonic forebrain, called prosencephalon. In this disorder the forebrain fails to divide into the double lobes of the cerebral hemisphere. As a result, the single-lobed brain structure is formed and severe skull and facial defects appear. In most of the cases, the malformations take a severe shape leading to the death of the child before birth. In some cases, the babies are born with less severe deformities and have normal or near-normal brain development and facial deformities that have an effect on the eyes, nose and upper lip.

What is Holoprosencephaly

What is the Treatment for Holoprosencephaly?

Although there is not standard course of treatment for the disorder, but the treatment can be symptomatic and supportive.

What is Holoprosencephaly

Prognosis for Holoprosencephaly

The prognosis for holoprosencephaly depends on the severity of the brain and facial deformities.

Image courtesy: Getty Images

Read more on Understand Holoprosencephaly.

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