Vaccine research for dengue was started in the 1940s by Sabin and colleagues. There have been several attempts to make a successful vaccine but this objective has not been realized. We know a lot about virus and disease, but no vaccine has been developed that is approved for use till now.
There are several problems in making a successful dengue vaccine.
Currently a vaccine is undergoing clinical trial in the USA which will protect against all four dengue viruses, DENV-1, DENV-2, DENV-3 and DENV-4. But the safety and effectiveness of the vaccine remains to be proven.
Read articles and Understand dengue
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