What are the complications of Respiratory Distress Syndrome?

Depending on the severity of an infant's RDS, he or she may develop other medical problems.

Lung Complications

Lung complications may include a collapsed lung (atelectasis), leakage of air from the lung into the chest cavity (pneumothorax), and bleeding in the lung (hemorrhage).
Some of the life-saving treatments used for RDS may cause bronchopulmonary dysplasia, another breathing disorder.

Blood and Blood Vessel Complications

Infants who have RDS may develop sepsis, an infection of the bloodstream. This infection can be life threatening.

Lack of oxygen may prevent a fetal blood vessel called the ductus arteriosus from closing after birth as it should. This condition is called patent ductus arteriosus, or PDA.

The ductus arteriosus connects a lung artery to a heart artery. If it remains open, it can put strain on the heart and increase blood pressure in the lung arteries.

Other Complications

Complications of RDS also may include blindness and other eye problems and a bowel disease called necrotizing enterocolitis (EN-ter-o-ko-LI-tis). Infants who have severe RDS can develop kidney failure.

Some infants who have RDS develop bleeding in the brain (intraventricular hemorrhage). This can delay mental development. It also can cause mental retardation or cerebral palsy.