What is Osteogenesis Imperfecta? - Find more information and articles related to Osteogenesis Imperfecta at onlymyhealth.com
The prognosis of osteogenesis imperfecta for a person varies depending on the severity of symptoms. Despite restricted activity, most adults and children with OI lead productive and successful lives.
The majority of OI is caused by a single dominant mutation in one of two type I collagen genes: COL1A1 or COL1A2. The COL1A1 and COL1A2 genes provide instructions for making proteins that are used to create a larger molecule called type I collagen.
Osteogenesis imperfect can be found in 1 in every 20,000 individuals. The disorder occurs with equal frequency among both the genders and racial and ethnic groups.
OI or brittle bone disease is a genetic disorder that causes the bones to breasl easily with or without much trauma.