Now you can Treat Diabetes with Cancer Drug, says Study

By  , Agency News
Sep 18, 2013
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Quick Bites

  • Diabetes treatment gets a new helping hand from cancer drugs.
  • There was an attempt to see if the liver would respond to insulin.
  • The drug is used to treat metastatic colorectal cancer.
  • Proteins involved in this pathway could be used for new diabetes therapies.

cancer drug to treat diabetesNew cancer drug have been found in a research that has the potential to treat diabetes. Researchers at the Stanford University School of Medicine have discovered a molecular pathway which is a series of interaction among proteins which are involved in the development of diabetes.


The study which was done in mice was to identify a previously unexpected link that was between a low oxygen conditions called hypoxia and also the ability of the cells in the liver to respond to insulin. The drug, (marketed as Eylea or Zaltrap), is used to treat metastatic colorectal cancer and a form of macular degeneration. This drug is a member of the family of proteins that are helpful to inhibit the vascular endothelial growth factor. This works by blocking the growth of the blood vessels into tumors and starve them of oxygen.


Calvin Kuo, MD, PhD, professor of medicine said, "We were surprised to find that this drug currently used in patients for cancer treatment had beneficial effects on diabetes in laboratory mice and could, potentially, in humans. Proteins involved in this pathway could also be targeted for the development of new diabetes therapies," Giaccia, who also is a professor and director of radiation oncology.”


It was published in Nature Medicine.


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