New research suggests that by transferring the vital insulin producing cells from the pancreas to the eye, the eye serves as a window through which health reports can be obtained. The endocrine part of the pancreas, known as the Islets of Langerhans, produces and secretes insulin which is the hormone that regulates blood sugar levels. After eating a meal when hormone is released into the blood at an amount that is in direct proportion to the amount of food which is indigested, the blood insulin levels vary from one meal to the next and also between individuals.
For a person who is obese large amounts of insulin are required to compensate for the high consumption of food and insensitivity to the hormone. This Islets of Langerhands try to adapt themselves to this condition by increasing the number of insulin-producing beta cells or even modulating their individual secretion of insulin in response to the intake of sugar.
The plasticity here is required to maintain the normal blood sugar levels and when it becomes dysfunctional it leads to diabetes. The biggest obstacle to study the workings of the Islet of Langerhans and how they adapt to individual conditions is the inaccessibility.
This could change as reporters have now found a new way to study the insulin producing beta cells y transferring the Islets of Langerhans to the eye.
Per-Olof Berggren, professor of experimental endocrinology at Karolinska Institutet's Department of Molecular Medicine and Surgery, and director of the Rolf Luft Research Centre for Diabetes and Endocrinology, said that they're now able to really study the insulin-producing beta-cells in detail in a way that wasn't possible before.
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