Now, we may know where epilepsy comes from. Australian scientists in collaboration with a US team used advanced gene technology to discover new genes and genetic mutation that causes severe childhood epilepsies.
Lead researcher Sam Berkovic, Director of the Epilepsy Research Centre at the University of Melbourne and Melbourne's Austin Hospital said that the research provide answers to patients and families who previously had little or no idea where epilepsy had come from. It would provide a pathway to treating epilepsy. It is one of the most frustrating things for parents who often have a belief that they've done something wrong that caused this disease.
By using the latest genetic techniques to sequence and analyse DNA of 4,000 epilepsy patients and their relatives, the study known called Epi4Ks shared DNA sequences and patient information among dozens of research institutions. The researchers compared the exomes, or the complete sets of genes, of 264 children with the sequences of their parents who do not have epilepsy. Differences in the sequences of parents and children were analysed to identify potential disease-causing mutations.
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