Prognosis of Syphilis

By  , Expert Content
Sep 21, 2011

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Syphilis is a common sexually transmitted disease. It can be difficult to diagnose as many of its signs and symptoms are difficult to differentiate from those of other diseases but it can be easily treated and cured if diagnosed in the early stages. Read on to know more on the prognosis of syphilis.


  • Signs and symptoms of syphilis vary depending on the stage of infection. The symptoms are relatively mild in the primary stages of infection, there are more notable systemic symptoms in the secondary stage of syphilis and significant neurological and cardiovascular involvement can occur in tertiary stage of the disease.
  • Syphilis can be easily treated with antibiotics in the primary and secondary stages. Penicillin is considered as the drug of choice unless you are allergic to it. Use of penicillin for treatment of syphilis has been able to control the spread of this common sexually transmitted disease but eradication of the disease has not been successful.
  • If the infection is not treated appropriately in the early stages (primary or secondary syphilis), it can progress to a more severe form of the disease known as tertiary syphilis. Tertiary syphilis can affect different parts such as the brain, nerves, eyes, heart, bones, skin or blood vessels and cause serious conditions such as stroke, paralysis, blindness or even death.
  • Prognosis of tertiary syphilis is less optimistic. Significant numbers of patients with tertiary syphilis show positive response to antibiotic therapy. But long-term health problems and complication are likely despite appropriate therapy.
  • People who have syphilis or other genital ulcer diseases are at higher risk of HIV. Besides this the risk of progression to neurosyphilis with complications is increased in people who are HIV positive.
  • Congenital syphilis is the most serious complication of syphilis in women. If a mother is not treated, her baby can get infected and it can cause complications such as late abortion, stillbirth, or even death soon after delivery.


Read more articles on Syphilis Diagnosis and Prognosis



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