A new study has confirmed that stem cells from the human olfactory ecto-mesenchymal system in the nose can help in treating brain disorders. The human olfactory ecto-mesenchymal system of the nose is the region which perceives smell. This research was carried out by a team led by Emmanuel Nivet of the Salk Institute for Biological Studies in La Jolla.
Nivet used mice as the sample for the study to try and prove that nose stem cells can in fact be used to heal that part of the brain that has been damaged and has consequently led to a disorder. The hippocampal region of the brain of the mice used as sample was damaged. When nose stem cells were transplanted into the brain, it was observed that the cells travelled to the damaged part of the brain and triggered the regeneration of cells. The olfactory ecto-mesenchymal cells also transformed into nerve cells at the site of injury.
It is being hoped that this new study can aid in helping people cope with memory loss and learning disorders as the treated mice had shown considerable development in their ability to learn and regain memory during the study.
Nose stem cells can also provide information regarding brain disorders such as schizophrenia that can help in further research and understanding of the disease. The olfactory stem cells can be obtained from the patient with the help of a simple biopsy and they could hold the key for both developmental and degenerative diseases.
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