Krabbe Disease - Get information and read articles on Krabbe Disease signs, symptoms, causes, treatment, prevention and diagnosis at onlymyhealth.com, your complete health guide.
In most cases, the signs and symptoms of Krabbe disease appear during the first few months of life. They begin gradually and progressively worsen.
Prognosis of Krabbe disease may be significantly better for children who receive umbilical cord blood stem cells before the onset of the disease or during the early phase of bone marrow transplantation.
Generally, treatment for Krabbe disease is symptomatic and supportive. Physical therapy may help maintain or increase muscle tone and circulation. If it develops in infants, the result is mostly death.
Causes of Krabbe Disease are deficiency of galactocerebrosidase, an essential enzyme for myelin metabolism.
Infants are at a risk of developing krabble disease, with onset before age 6 months, but can occur in adolescence or adulthood.
Krabbe disease is a rare, inherited degenerative disorder of the central and peripheral nervous systems that destroys the myelin, a protective coating of nerve cells inside the brain and throughout the nervous system.