|In more than 99.9 percent of cases of Rett Syndrome, the genetic mutation is spontaneous.|
Random mutations are usually not inherited or passed from one generation to the next. In a very small percentage of families—about 1 percent—Rett mutations are inherited and passed on by female carriers. Scientists are working to learn more about these families to understand how this inherited mutation arises.
Werner syndrome is inherited in an autosomal recessive pattern, which means both copies of the WRN gene in each cell have mutations.read more
Waardenburg syndrome is usually inherited in an autosomal dominant pattern, which means one copy of the altered gene in each cell is sufficient to cause the disorder.read more