How can one prevent Langerhan’s Cell Histiocytosis or Histiocytosis?

By  ,  Onlymyhealth editorial team
Jul 03, 2014

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Quick Bites

  • The number of immune cells increases in histiocytosis.
  • In this condition the autoimmune cells attack the body.
  • The symptoms of the disease vary according to age.
  • The patient must quit smoking to prevent the disease.

What is Histiocytosis?

Histiocytosis is a name given to a group of syndromes in which there is an increase in the number of immune cells called histiocytes.
It can be classified into 3 major classes of histiocytoses:

  • Langerhans cell histiocytosis also known as histiocytosis X
  • Maligant histiocytosis syndrome
  • Non-langerhans cell histiocytosis

Langerhans cell histiocytosis Prevention

What are the Causes of Langerhans Histiocytosis?

Histiocytosis is considered to be more a cancer like condition. However, in a recent research it was shown that it is an autoimmune phenomenon in which immune cells attack the body by mistake instead of fighting the infections. The extra immune cells can take form of tumours which have affect on several parts of the body including bones, skull, etc.


Langerhans cell histiocytosis Prevention


Histiocytosis X affects the entire body hence, is called systemic disorder. The symptoms of the disorder vary according to the age of the patients. Symptoms in young children may include:

  • Abdominal pain
  • Bone pain
  • Delay in puberty
  • Dizziness
  • Drainage from the ear
  • Protruding eyes
  • Irritation
  • Failure to grow
  • Fever
  • Frequent urination
  • Headache
  • Jaundice
  • Limping
  • Mental deterioration
  • Rash
  • Seizures
  • Short stature
  • Swollen lymph glands
  • Vomiting
  • Weight loss
  • Symptoms in adults may include:
  • Pain in the bones
  • Pain in the chest
  • Cough
  • Fever
  • Uneasiness
  • Frequent urination
  • Rash
  • Breathlessness
  • Weight loss



The disease can be treated with corticosteroids which suppress the immune function. If a patient is a smoker, it may worsen the condition.

Children suffering from the disorder may be given medication which may includes:

  • Cyclophosphamide
  • Etoposide
  • Methotrexate
  • Vinblastine



As the cause of Langerhans' cell histiocytosis is yet to be discovered there are no substantial ways to prevent it. However, as smoking worsens the condition of a patient and the disorder develops in lungs, it is always best to quit smoking. This will prevent the diseases from developing into a serious condition.

Image courtesy: getty images

Read more on Langerhans cell histiocytosis.

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