Findings of a latest have found that people who have mutations in hair keratin genes are more likely to suffer from cavities.
Researcher Maria Morasso and colleagues at the US National Institutes of Health found abnormalities in the structure of tooth enamel from individuals with keratin mutations. The abnormality is also believed to cause weakness.
According to the researchers, the results of this study established a link between hair disorders and cavity formation.
It was found during this study that epithelial hair keratins, which are important for maintaining the integrity of the sheaths that give support to the hair shaft, are expressed in the enamel organ and are essential organic components of mature enamel.
In research, 386 children and 706 adults were studied and it was found that individuals who had known hair disorders associated polymorphisms in the gene encoding keratin 75 are prone to increased dental caries.
The analysis carried out on teeth of individuals carrying one of the variants showed an altered enamel structure and a marked reduction of enamel hardness. This suggested that a functional keratin network is needed for the mechanical stability of tooth enamel.
This study has been published in the Journal of Clinical Investigation.
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