A study published in the journal PLOS ONE claim to have discovered a ‘master regulator’ gene that, when repressed in cancer cells, halt tumour growth and stops them from enlarging and metastasizing.
The discovery could be the key to develop a new treatment for tumours resistant to current drugs, stated Linda Resar from the Johns Hopkins University School of Medicine. It was found that the gene is normally turned off in adult cells, but it is abnormally active during embryonic development and in all highly aggressive tumours. If the gene is switched off, the appearance and behaviour of the aggressive cancer cells change dramatically.
The researchers have been studying the master regulator's family, known as high mobility group or HMG genes, since 10 years.
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