According to a recent study, immature myeloid cells or M-MDSC can help in shutting arthritis down. With the help of a mouse model of rheumatoid arthritis, scientists have been able to discover that the M-MDSCs can effectively treat the disease in humans.
In a recent report, it was shown that M-MDSCs can inhibit T cell proliferation, B cell proliferation as well as antibody production. This results in experience of improvements in the arthritic mice along with betterment of symptoms.
The researchers hope that the study will lead to a better understanding of the potential that MDSC’s have in cell-based therapies against autoimmune diseases. Cellular therapies that use cells from the immune system have been revolutionizing clinical treatment for cancer as well as other diseases, though they typically use T cells.
As for the new studies, they not only identify the potential role of myeloid derived M-MDSCs in cellular therapies, but they also demonstrate the different approach types that may be effective in autoimmune diseases.
The study has been published in the Journal of Leukocyte Biology.
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Article courtesy: DNA
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