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Reasons for Low Platelet Count in Dengue Fever

By  ,  Onlymyhealth editorial team
Apr 06, 2011
4.8 / 5(4 Ratings)
Quick Bites

  • Dengue virus can induce bone marrow suppression.
  • Dengue virus can even bind to platelets of human blood.
  • Another reasons is vascular endothelial cells getting infected.
  • Antibodies production after infection is another reason.

More

Blood platelets also known as thrombocytes play an important role in your body. These cell fragments are natural source of growth and play basic role in process of hemostasis (preventing bleeding from damaged blood vessel) as well.

 

low platelets

 

Normal platelet count in a micro litre of human blood is 150000 to 450000. Slight decrease in the platelet count does not contribute to the disease but when it is below 50,000 per micro litre, thrombocytopenia occurs. Low platelet count in dengue fever can be very dangerous.

The reasons for low platelet count in dengue fever are as follows.

  • Dengue virus, the main cause of dengue fever induces bone marrow suppression. Since bone marrow is the manufacturing centre of blood cells its suppression causes deficiency of blood cells leading to low platelet count. Anaemia and spontaneous severe bleeding are the other resultant factors of bone marrow suppression.
  • Studies suggest that dengue virus can even bind to platelets of human blood in the presence of virus-specific antibody.

 

dengue fever

 

  • When vascular endothelial cell that are infected with dengue virus gets combined with platelets they tend to destroy platelets. This is one of the major causes of low platelet count in dengue fever.
  • Even the antibodies that are produced after infection of dengue virus can contribute in destruction of platelets, thus lowering the platelet count.

 

 

Low platelet count in dengue fever may lead to life-threatening condition known as hemorrhagic dengue fever that is categorised by spontaneous bleeding tendency and shock.

(Images:Getty)

Read more articles on Dengue.

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Comments
  • hebzibha09 Jan 2013
    my sister is affected with dengue fever now. she got platelet count of 67000. is it dangerous?
  • sangeetha.r19 Nov 2012
    thank u. a very detailed article. Now i have all the information i wanted.
  • mrityunjoy roy01 Nov 2012
    age of patient is 15+.he has a low platelet count .. it is 22000 now.. but WBC,RBC count is normal.. Ns1 is not present. is it necessary to give platelet now?
  • pandurang phad29 Oct 2012
    is there any associatn between high dose antibiotics as ceftriaxone and platelets in viral hemorrhagic fever.
  • moorthy10 Oct 2012
    good information
  • Seema18 Sep 2012
    Are the symptoms of Dengue Fever similar to any other medical condition? what are the specific signs?
  • CHANDRIMA DAS31 Aug 2012
    MY NIECE HAS COME DOWN TO INDIA RECENTLY FROM ENGLAND,EVERY SECONED SHE IS SCARED ABOUT THE DEADLY DISEASE ,HOW CAN I MAKE HER UNDERSTAND AS BECAUSE SHE IS BIT OVER REACTING AT THE SAME TIME PSYCOLOGICAL PROBLEMS ALSO DEVELOPING RAPIDLY.REGARDS-CHANDRIMA
  • Name17 Aug 2012
    Dear kiran, yes it can be very dangerous..wonder if u have heard about the homeopathic treatment with papaya leaves and stem juice.. it works as magic drug in most cases..u 2 can give it a try... it helps raise platelet count very fast, within 3 to 4 days itself...(self-experience).
  • kiran06 Aug 2012
    Three days back my sister platelet count is 85000 now it is redused to 19000 we r admitted in hospital, is it dangerous please clarify
  • Deepthi20 Jul 2012
    Wat is the antibotic used for dengue virus treatment.